1,2-Bis(2-Nitrophenoxy)ethane

Base Information

• Chemical Name: 1,2-Bis(2-Nitrophenoxy)ethane
• CAS No.: 51661-19-9
• Molecular Formula: C14H12N2O6
• Molecular Weight: 304.259
• Hs Code.: 2909309090
• European Community (EC) Number: 449-470-2,610-713-4
• NSC Number: 698149
• DSSTox Substance ID: DTXSID30963836
• Nikkaji Number: J1.576.441D
• Wikidata: Q82945747
• ChEMBL ID: CHEMBL1370295
• Mol file: 51661-19-9.mol

Synonyms:51661-19-9;1,2-Bis(o-nitrophenoxy)ethane;1,2-Bis(2-Nitrophenoxy)ethane;1-nitro-2-[2-(2-nitrophenoxy)ethoxy]benzene;Ethylene Glycol Bis(2-nitrophenyl) Ether;NSC698149;Bis(2-nitrophenoxy)ethane;1,1'-[ethane-1,2-diylbis(oxy)]bis(2-nitrobenzene);4742-89-6;Bis(o-nitrophenoxy)ethane;MLS000851132;1,2-di(o-nitrophenoxy)ethane;SCHEMBL9187561;CHEMBL1370295;DTXSID30963836;HMS2800E15;2-BIS(2-NITROPHENOXY)ETHANE;MFCD00024226;STL368292;AKOS000441607;NSC-698149;AS-59835;NCI60_035106;SMR000457375;2,2'-(Ethylenedioxy)bis(1-nitrobenzene);E1006;FT-0640013;EC 449-470-2;T72557;A871210;1,1'-[1,2-Ethanediylbis(oxy)]bis(2-nitrobenzene);Benzene, 1,1'-[1,2-ethanediylbis(oxy)]bis[2-nitro-;Hydroxy(2-(2-(2-(hydroxy(oxido)amino)phenoxy)ethoxy)phenyl)azane oxide

Chemical Property of 1,2-Bis(2-Nitrophenoxy)ethane

Chemical Property:

• Appearance/Colour: Yellow Crystalline Solid
• Vapor Pressure: 1.06E-09mmHg at 25°C
• Melting Point: 167-170 °C
• Refractive Index: 1.609
• Boiling Point: 501.7 °C at 760 mmHg
• Flash Point: 226.1 °C
• PSA: 110.10000
• Density: 1.37 g/cm³
• LogP: 4.00720
• Storage Temp.: 2-8°C
• Solubility.: Ethanol, Tetrahydrofuran
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 304.06953611
• Heavy Atom Count: 22
• Complexity: 345

Purity/Quality:

99.9% ^*data from raw suppliers

1,2-Bis(2-nitrophenoxy)ethane ^*data from reagent suppliers

Safty Information:

• Statements: 23/24/25-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)[N+](=O)[O-])OCCOC2=CC=CC=C2[N+](=O)[O-]

Technology Process of 1,2-Bis(2-Nitrophenoxy)ethane

There total 10 articles about 1,2-Bis(2-Nitrophenoxy)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-(2-chloroethoxy)-2-nitrobenzene (102236-25-9) + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1,2-bis(2-nitrophenoxy)ethane (51661-19-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 140 ℃; for 4h;

DOI:10.5935/0103-5053.20130276

Reference yield: 90.0%

1-Bromo-2-chloroethane (107-04-0) + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1,2-bis(2-nitrophenoxy)ethane (51661-19-9)

Guidance literature:

2-hydroxynitrobenzene; With potassium carbonate; In N,N-dimethyl-formamide;

1-Bromo-2-chloroethane; With potassium iodide; In N,N-dimethyl-formamide; Heating;

at 110 ℃; for 2h;

DOI:10.1002/ejoc.202100948

Reference yield: 78.0%

ethylene dibromide (106-93-4) + 2-hydroxynitrobenzene (88-75-5,78813-12-4) → 1,2-bis(2-nitrophenoxy)ethane (51661-19-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; acetonitrile; at 100 ℃; for 6h;

DOI:10.1021/acs.inorgchem.5b00106

upstream raw materials:

potassium 4-nitrophenolate

1,2-dichloro-ethane

ethylene dibromide

sodium o-nitrophenate

Downstream raw materials:

1,2-Bis(2-aminophenoxy)ethane

1,2-bis-(2,4-dinitro-phenoxy)-ethane

1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis acetoxymethyl ester

[(2-{2-[2-(bis-methoxycarbonylmethylamino)-5-methylphenoxy]ethoxy}-4-formyl-5-methyl-phenyl)methoxycarbonylmethylamino]acetic acid methyl ester