5-Bromo-2-fluoroaniline

Base Information Edit

Chemical Name:5-Bromo-2-fluoroaniline
CAS No.:2924-09-6
Molecular Formula:C6H5BrFN
Molecular Weight:190.015
Hs Code.:29214990
DSSTox Substance ID:DTXSID40951845
Nikkaji Number:J3.484.453D
Wikidata:Q72455683
Mol file:2924-09-6.mol

Synonyms:5-Bromo-2-fluoroaniline;2924-09-6;5-bromo-2-fluorobenzenamine;2-Fluoro-5-Bromoaniline;BENZENAMINE, 5-BROMO-2-FLUORO-;MFCD03094181;5-bromo-2-fluorophenylamine;5-Bromo-2-fluoro-phenylamine;5-bromo-2fluoroaniline;5-bromo-2-fluoro aniline;SCHEMBL109380;DTXSID40951845;ADWKOCXRCRSMLQ-UHFFFAOYSA-N;5-Bromo-2-fluoroaniline, AldrichCPR;AKOS008901335;AC-3656;CS-W015919;PS-8399;SY012792;AM20060791;B3043;FT-0600939;FT-0649049;FT-0653558;EN300-42851;Z406521002

Suppliers and Price of 5-Bromo-2-fluoroaniline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-2-fluoroaniline
1g
$ 45.00

TCI Chemical
5-Bromo-2-fluoroaniline >95.0%(GC)
25g
$ 46.00

TCI Chemical
5-Bromo-2-fluoroaniline >95.0%(GC)
5g
$ 15.00

SynQuest Laboratories
5-Bromo-2-fluoroaniline 98%
25 g
$ 23.00

SynQuest Laboratories
5-Bromo-2-fluoroaniline 98%
10 g
$ 10.00

SynQuest Laboratories
5-Bromo-2-fluoroaniline 98%
100 g
$ 55.00

Matrix Scientific
5-Bromo-2-fluoroaniline 98%
25g
$ 28.00

Matrix Scientific
5-Bromo-2-fluoroaniline 98%
100g
$ 76.00

Matrix Scientific
5-Bromo-2-fluoroaniline 98%
500g
$ 228.00

Frontier Specialty Chemicals
5-Bromo-2-fluoroaniline 98%
25g
$ 259.00

Total 81 raw suppliers

Chemical Property of 5-Bromo-2-fluoroaniline Edit

Chemical Property:

Vapor Pressure:0.0843mmHg at 25°C
Melting Point:27℃
Refractive Index:1.596
Boiling Point:225.9 °C at 760 mmHg
PKA:2.13±0.10(Predicted)
Flash Point:90.4 °C
PSA：26.02000
Density:1.694 g/cm³
LogP:2.75160
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Water Solubility.:Slightly soluble in water.
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:188.95894
Heavy Atom Count:9
Complexity:99.1

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-2-fluoroaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s): T, Xi
Hazard Codes:T,Xi,Xn
Statements: 22-36-52-36/37/38-20/21/22
Safety Statements: 26-60-36/37-9

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Br)N)F
Uses 5-Bromo-2-fluoroaniline is used as pharmaceutical intermediate.

Technology Process of 5-Bromo-2-fluoroaniline

There total 6 articles about 5-Bromo-2-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 364-73-8
4-Bromo-1-fluoro-2-nitrobenzene

: 2924-09-6
5-bromo-2-fluoroaniline

Guidance literature:: With iron; ammonium chloride; In ethanol; water; at 70 ℃; for 24h;

Reference yield:

: 364-73-8
4-Bromo-1-fluoro-2-nitrobenzene

: 348-54-9
2-Fluoroaniline

: 2924-09-6
5-bromo-2-fluoroaniline

Guidance literature:: With 5%-palladium/activated carbon; hydrazine hydrate; In methanol; at 80 ℃; for 0.0833333h; Overall yield = 37 %;
DOI:10.1055/s-0033-1339025