2,3-Difluoro-4-ethoxybenzeneboronic acid

Base Information Edit

Chemical Name:2,3-Difluoro-4-ethoxybenzeneboronic acid
CAS No.:212386-71-5
Molecular Formula:C8H9BF2O3
Molecular Weight:201.965
Hs Code.:2931900090
Mol file:212386-71-5.mol

Synonyms:Boronicacid, (4-ethoxy-2,3-difluorophenyl)- (9CI);

Suppliers and Price of 2,3-Difluoro-4-ethoxybenzeneboronic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-Difluoro-4-ethoxyphenylboronicacid
1g
$ 75.00

TRC
2,3-Difluoro-4-ethoxyphenylboronicacid
250mg
$ 55.00

TCI Chemical
4-Ethoxy-2,3-difluorophenylboronic Acid (contains varying amounts of Anhydride)
1g
$ 38.00

TCI Chemical
4-Ethoxy-2,3-difluorophenylboronic Acid (contains varying amounts of Anhydride)
5g
$ 116.00

SynQuest Laboratories
2,3-Difluoro-4-ethoxybenzeneboronic acid 98%
1 g
$ 85.00

SynQuest Laboratories
2,3-Difluoro-4-ethoxybenzeneboronic acid 98%
250 mg
$ 25.00

Matrix Scientific
2,3-Difluoro-4-ethoxyphenylboronic acid
1g
$ 24.00

Matrix Scientific
2,3-Difluoro-4-ethoxyphenylboronic acid
5g
$ 79.00

Labseeker
2,3-Difluoro-4-ethoxybenzeneboronicacid 98%
50g
$ 700.00

Crysdot
(4-Ethoxy-2,3-difluorophenyl)boronicacid 95+%
10g
$ 127.00

Total 118 raw suppliers

Chemical Property of 2,3-Difluoro-4-ethoxybenzeneboronic acid Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:151-154 °C
Refractive Index:1.484
Boiling Point:315.98 °C at 760 mmHg
PKA:7.69±0.58(Predicted)
Flash Point:144.9 °C
PSA：49.69000
Density:1.299 g/cm³
LogP:0.04330
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:soluble in Methanol
Water Solubility.:145mg/L at 20℃

Purity/Quality:

99% ^*data from raw suppliers

2,3-Difluoro-4-ethoxyphenylboronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Uses suzuki reaction

Technology Process of 2,3-Difluoro-4-ethoxybenzeneboronic acid

There total 8 articles about 2,3-Difluoro-4-ethoxybenzeneboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 7647-01-0,15364-23-5
hydrogenchloride

: 121-43-7,63156-11-6
Trimethyl borate

: 1-ethoxy-2,3-difluorobenzene

: 212386-71-5
(4-ethoxy 2,3-difluorophenyl)boronic acid

Guidance literature:: 1-ethoxy-2,3-difluorobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -70 - -60 ℃; for 1h; Inert atmosphere;

hydrogenchloride; Trimethyl borate; In tetrahydrofuran; hexane; water; at -30 ℃;

Reference yield: 80.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 1-ethoxy-2,3-difluorobenzene

: 212386-71-5
(4-ethoxy 2,3-difluorophenyl)boronic acid

Guidance literature:: 1-ethoxy-2,3-difluorobenzene; With n-butyllithium; In tetrahydrofuran; at -60 ℃; for 0.5h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; at -10 ℃; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; pH=1; Inert atmosphere;

Reference yield: 71.0%

: 156573-09-0
1-bromo-4-ethoxy-2,3-difluorobenzene

: 121-43-7,63156-11-6
Trimethyl borate

: 212386-71-5
(4-ethoxy 2,3-difluorophenyl)boronic acid

Guidance literature:: 1-bromo-4-ethoxy-2,3-difluorobenzene; With n-butyllithium; In tetrahydrofuran; at -70 ℃; for 2h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; at -70 - 20 ℃; for 16h;

With hydrogenchloride; In tetrahydrofuran; water;