3-(2-Chloroethyl)quinazolin-4(3H)-one

Base Information

Chemical Name:3-(2-Chloroethyl)quinazolin-4(3H)-one
CAS No.:2940-68-3
Molecular Formula:C10H9ClN2O
Molecular Weight:208.647
Hs Code.:
European Community (EC) Number:651-593-3
DSSTox Substance ID:DTXSID50403865
Nikkaji Number:J431.839K
Wikidata:Q82207721
Mol file:2940-68-3.mol

Synonyms:3-(2-Chloroethyl)quinazolin-4(3H)-one;2940-68-3;3-(2-chloroethyl)-3,4-dihydroquinazolin-4-one;3-(2-chloroethyl)quinazolin-4-one;4(3H)-Quinazolinone, 3-(2-chloroethyl)-;3-(2-CHLORO-ETHYL)-3H-QUINAZOLIN-4-ONE;SCHEMBL874574;DTXSID50403865;NJCVGJQMNUHBCF-UHFFFAOYSA-N;CAA94068;AKOS009293563;3-(2-chloroethyl)-4(3H)-quinazolinone;3-(2-chloroethyl)quinazoline-4(3H)-one;3-(2-chloroethyl) quinazoline-4(3H)-one;3-(2-chloroethyl)quinazoline-4 (3H)-one;3-(2-chloroethyl) quinazoline-4 (3H)-one;CS-0230798;EN300-105650

Suppliers and Price of 3-(2-Chloroethyl)quinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2-chloroethyl)-3,4-dihydroquinazolin-4-one
10mg
$ 45.00

American Custom Chemicals Corporation
3-(2-CHLORO-ETHYL)-3H-QUINAZOLIN-4-ONE 95.00%
5MG
$ 499.15

AK Scientific
3-(2-Chloroethyl)quinazolin-4(3H)-one
5g
$ 2889.00

AK Scientific
3-(2-Chloroethyl)quinazolin-4(3H)-one
2.5g
$ 1996.00

Total 9 raw suppliers

Chemical Property of 3-(2-Chloroethyl)quinazolin-4(3H)-one

Chemical Property:

PSA：34.89000
LogP:1.63530
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:208.0403406
Heavy Atom Count:14
Complexity:255

Purity/Quality:

97% ^*data from raw suppliers

3-(2-chloroethyl)-3,4-dihydroquinazolin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C=N2)CCCl

Technology Process of 3-(2-Chloroethyl)quinazolin-4(3H)-one

There total 5 articles about 3-(2-Chloroethyl)quinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 2981-86-4
3-(2-hydroxyethyl)quinazolin-4(3H)-one

: 2940-68-3
3-(2-Chloroethyl)-4(3H)-quinazolinone

Guidance literature:: With thionyl chloride; at 85 ℃;

Reference yield: 81.0%

: 49667-81-4
2-amino-N-(2-hydroxyethyl)benzamide

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 2940-68-3
3-(2-Chloroethyl)-4(3H)-quinazolinone

Guidance literature:: With trichlorophosphate; for 0.25h; Heating;

Reference yield:

: 491-36-1
4-Hydroxyquinazoline

: 2940-68-3
3-(2-Chloroethyl)-4(3H)-quinazolinone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 70 °C

2: thionyl chloride / tetrahydrofuran / 20 °C / Cooling with ice

With thionyl chloride; potassium carbonate; In tetrahydrofuran; acetonitrile;