3-(4-chlorophenyl)-5-phenyl-1H-pyrazole

Base Information

• Chemical Name: 3-(4-chlorophenyl)-5-phenyl-1H-pyrazole
• CAS No.: 30152-32-0
• Molecular Formula: C15H11ClN2
• Molecular Weight: 254.719
• DSSTox Substance ID: DTXSID10357835
• Nikkaji Number: J1.702.283K,J3.151.835K
• Wikidata: Q82137995
• ChEMBL ID: CHEMBL218059
• Mol file: 30152-32-0.mol

Synonyms:3-(4-chlorophenyl)-5-phenyl-1H-pyrazole;30152-32-0;ZINC00434359;Enamine_001573;CHEMBL218059;SCHEMBL6231163;DTXSID10357835;HMS1398H11;3-(4-chlorophenyl)-5-phenylpyrazol;AKOS001034435;Z56802839

Chemical Property of 3-(4-chlorophenyl)-5-phenyl-1H-pyrazole

Chemical Property:

• PSA: 28.68000
• LogP: 4.39710
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 254.0610761
• Heavy Atom Count: 18
• Complexity: 257

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Chlorophenyl)-5-phenyl-1H-pyrazole 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NNC(=C2)C3=CC=C(C=C3)Cl

Technology Process of 3-(4-chlorophenyl)-5-phenyl-1H-pyrazole

There total 32 articles about 3-(4-chlorophenyl)-5-phenyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-(4-chlorophenyl)-1-phenylprop-2-en-1-one (956-04-7) → 3-(4?'-chlorophenyl)-5-phenyl-1H-pyrazole (30152-32-0)

Guidance literature:

With iodine; potassium carbonate; toluene-4-sulfonic acid hydrazide; In ethanol; at 75 ℃; for 2h; regioselective reaction; Green chemistry;

DOI:10.1016/j.tetlet.2016.05.020

Reference yield: 91.0%

C22H19ClN2O2S → 3-(4?'-chlorophenyl)-5-phenyl-1H-pyrazole (30152-32-0)

Guidance literature:

With potassium carbonate; In acetonitrile; at 25 ℃; Reagent/catalyst; Irradiation;

DOI:10.1002/adsc.201701200

Reference yield: 87.0%

semicarbazide hydrochloride (563-41-7) + trans-1-(p-chlorophenyl)-3-phenyl-2,3-epoxy-1-propanone (32157-73-6,40327-53-5,67175-58-0,130007-85-1) → 3-(4?'-chlorophenyl)-5-phenyl-1H-pyrazole (30152-32-0)

Guidance literature:

In ethanol; at 40 - 50 ℃; for 0.5h;

DOI:10.1007/s00706-007-0829-5

upstream raw materials:

2-bromo-3-(4-chlorophenyl)-1-phenylprop-2-en-1-one

[3-(4-Chloro-phenyl)-5-hydroxy-5-phenyl-4,5-dihydro-pyrazol-1-yl]-phenyl-methanone

(4-Chloro-phenyl)-[3-(4-chloro-phenyl)-5-hydroxy-5-phenyl-4,5-dihydro-pyrazol-1-yl]-methanone

copper(I) phenylacetylenide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 30152-32-0 1H-Pyrazole, 3-(4-chlorophenyl)-5-phenyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send