4'-CHLORO-2,2-DIMETHYLPROPIOPHENONE

Base Information

Chemical Name:4'-CHLORO-2,2-DIMETHYLPROPIOPHENONE
CAS No.:30314-42-2
Molecular Formula:C11H13ClO
Molecular Weight:196.677
Hs Code.:2914700090
European Community (EC) Number:844-628-0
DSSTox Substance ID:DTXSID30456576
Wikidata:Q82279131
Mol file:30314-42-2.mol

Synonyms:t-butyl p-chlorophenyl ketone;tert-butyl 4-chlorophenyl ketone;1-(4-Chlorphenyl)-2,2-dimethyl-1-propanon;1-(4-chlorophenyl)-2,2-dimethyl-1-propanone;(4-chlorophenyl) tert-butyl ketone;QC-3370;p-chloropivalophenone;4'-CHLORO-2,2-DIMETHYLPROPIOPHENONE;

Suppliers and Price of 4'-CHLORO-2,2-DIMETHYLPROPIOPHENONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-chlorophenyl)-2,2-dimethylpropan-1-one
50mg
$ 110.00

Rieke Metals
4'-Chloro-2,2-dimethylpropiophenone 97%
5g
$ 1514.00

Rieke Metals
4'-Chloro-2,2-dimethylpropiophenone 97%
2g
$ 731.00

Rieke Metals
4'-Chloro-2,2-dimethylpropiophenone 97%
1g
$ 417.00

Matrix Scientific
4'-Chloro-2,2-dimethylpropiophenone 97%
5g
$ 1185.00

Matrix Scientific
4'-Chloro-2,2-dimethylpropiophenone 97%
1g
$ 385.00

Crysdot
1-(4-Chlorophenyl)-2,2-dimethylpropan-1-one 95+%
1g
$ 366.00

Crysdot
1-(4-Chlorophenyl)-2,2-dimethylpropan-1-one 95+%
5g
$ 1126.00

ChemScene
1-(4-Chlorophenyl)-2,2-dimethylpropan-1-one
5g
$ 1327.00

ChemScene
1-(4-Chlorophenyl)-2,2-dimethylpropan-1-one
1g
$ 442.00

Total 9 raw suppliers

Chemical Property of 4'-CHLORO-2,2-DIMETHYLPROPIOPHENONE

Chemical Property:

Vapor Pressure:0.005mmHg at 25°C
Boiling Point:274.68oC at 760 mmHg
Flash Point:150.8oC
PSA：17.07000
Density:1.078g/cm3
LogP:3.56880
Storage Temp.:2-8°C
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:196.0654927
Heavy Atom Count:13
Complexity:185

Purity/Quality:

99% ^*data from raw suppliers

1-(4-chlorophenyl)-2,2-dimethylpropan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)C1=CC=C(C=C1)Cl

Technology Process of 4'-CHLORO-2,2-DIMETHYLPROPIOPHENONE

There total 19 articles about 4'-CHLORO-2,2-DIMETHYLPROPIOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 106-39-8
bromochlorobenzene

: 630-19-3
pivalaldehyde

: 30314-42-2
1-(4-chlorophenyl)-2,2-dimethylpropan-1-one

Guidance literature:: bromochlorobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

pivalaldehyde; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

With iodine; potassium carbonate; In tert-butyl alcohol; for 5h; Reflux;
DOI:10.1016/j.tet.2011.12.023

Reference yield: 88.0%

: 99-91-2
para-chloroacetophenone

: 74-88-4
methyl iodide

: 30314-42-2
1-(4-chlorophenyl)-2,2-dimethylpropan-1-one

Guidance literature:: With potassium hydroxide; 18-crown-6 ether; In toluene; at 70 ℃; for 1h;

Reference yield: 80.0%

: 104-88-1
4-chlorobenzaldehyde

: 84379-72-6
1,3-dioxoisoindolin-2-yl 3,3-dimethylbutanoate

: 30314-42-2
1-(4-chlorophenyl)-2,2-dimethylpropan-1-one

Guidance literature:: With 3-(2,6-diisopropylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[d]thiazol-3-ium perchlorate; caesium carbonate; In dimethyl sulfoxide; at 60 ℃; for 4h; Inert atmosphere; Schlenk technique; Sealed tube;
DOI:10.1021/jacs.9b00880