Benzeneacetic acid, a-oxo-, propyl ester

Base Information

• Chemical Name: Benzeneacetic acid, a-oxo-, propyl ester
• CAS No.: 31197-63-4
• Molecular Formula: C11H12O3
• Molecular Weight: 192.214
• Mol file: 31197-63-4.mol

Synonyms:

Chemical Property of Benzeneacetic acid, a-oxo-, propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneacetic acid, a-oxo-, propyl ester

There total 18 articles about Benzeneacetic acid, a-oxo-, propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyl 2-oxo-2-phenylacetate (15206-55-0) + ethanol (64-17-5) → propyl 2-oxo-2-phenylacetate (31197-63-4)

Guidance literature:

With zinc oxide nanoparticles; at 100 ℃; for 24h; Time; Catalytic behavior;

DOI:10.1016/j.cattod.2019.08.053

Reference yield: 92.0%

propan-1-ol (71-23-8) + phenylglyoxylyl chloride (25726-04-9) → propyl 2-oxo-2-phenylacetate (31197-63-4)

Guidance literature:

With pyridine; In benzene; at 0 ℃; for 0.5h;

Reference yield: 90.0%

propan-1-ol (71-23-8) + 4,4,4-trifluoro-3-hydroxy-1-phenylbut-2-en-1-one (41463-86-9) → propyl 2-oxo-2-phenylacetate (31197-63-4)

Guidance literature:

With tert.-butylhydroperoxide; iodine; sodium carbonate; In 1,2-dichloro-ethane; at 60 ℃; for 7h;

DOI:10.1055/s-0036-1588833

upstream raw materials:

benzoyl cyanide

propan-1-ol

Benzoylformic acid

phenylglyoxylyl chloride

Downstream raw materials:

benzaldehyde

propionaldehyde

Refernces

• 1、 Xu, Jian,Peng, Yongzhen,Wang, Zhiguo,Hu, Yujing,Fan, Jiajie,Zheng, He,Lin, Xianfu,Wu, Qi. "Exploiting Cofactor Versatility to Convert a FAD-Dependent Baeyer–Villiger Monooxygenase into a Ketoreductase". supporting information. p. 14499 - 14503. Retrieved 2019/09/17.
• 2、 Ni, Ke,Meng, Ling-Guo,Ruan, Hongjie,Wang, Lei. "Controllable chemoselectivity in the coupling of bromoalkynes with alcohols under visible-light irradiation without additives: Synthesis of propargyl alcohols and α-ketoesters". supporting information. p. 8438 - 8441. Retrieved 2019/07/22.