Benzenesulfinyl chloride, 4-methoxy-

Base Information

• Chemical Name: Benzenesulfinyl chloride, 4-methoxy-
• CAS No.: 31401-23-7
• Molecular Formula: C7H7ClO2S
• Molecular Weight: 190.65
• DSSTox Substance ID: DTXSID80448027
• Nikkaji Number: J582.177K
• Mol file: 31401-23-7.mol

Synonyms:Benzenesulfinyl chloride, 4-methoxy-;31401-23-7;SCHEMBL6581229;p-Methoxybenzenesulfinyl chloride;DTXSID80448027

Chemical Property of Benzenesulfinyl chloride, 4-methoxy-

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 189.9855283
• Heavy Atom Count: 11
• Complexity: 143

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)S(=O)Cl

Technology Process of Benzenesulfinyl chloride, 4-methoxy-

There total 9 articles about Benzenesulfinyl chloride, 4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methoxybenzene (100-66-3) → p-methoxybenzenesulfinyl chloride (31401-23-7)

Guidance literature:

With thionyl chloride; Montmorillonite K-10 clay; In chloroform; at 50 ℃; for 2h;

DOI:10.1055/s-2001-17437

Reference yield:

methoxybenzene (100-66-3) → p-methoxybenzenesulfinyl chloride (31401-23-7) + bis(4-methoxyphenyl)sulfide (3393-77-9)

Guidance literature:

With bismuth(III) oxychloride; thionyl chloride; at 60 ℃; for 1h; Further Variations:; Reagents; Temperatures; reaction time; Product distribution;

Reference yield:

4,4'-dimethoxyphenyl disulfide (5335-87-5) → p-methoxybenzenesulfinyl chloride (31401-23-7)

Guidance literature:

With thionyl chloride;

DOI:10.1016/S0960-894X(00)00438-8

upstream raw materials:

4-Methoxybenzenethiol

sodium 4-methoxybenzenesulfinate

methoxybenzene

4-methoxybenzenesulfinic acid

Downstream raw materials:

4-(4-Methoxy-benzenesulfinyl)-2,3,5,6-tetramethyl-phenol

S-4-methoxyphenyl 4-methoxybenzenesulfinothioate

2-(p-methoxyphenylsulfonyl)-1-phenylpropene

sodium 4-methoxybenzenesulfinate

Refernces

• 1、 Bolm, Carsten,Ma, Ding,Shi, Peng,Tu, Yongliang,Wang, Chenyang. "Visible Light-Promoted Synthesis of β-Keto Sulfoximines from N-Tosyl-Protected Sulfoximidoyl Chlorides". . . Retrieved 2022/02/05.
• 2、 Mariz, Ronaldo,Poater, Albert,Gatti, Michele,Drinkel, Emma,Buergi, Justus J.,Luan, Xinjun,Blumentritt, Sascha,Linden, Anthony,Cavallo, Luigi,Dorta, Reto. "C2-symmetric chiral disulfoxide ligands in rhodium-catalyzed 1,4-addition: From ligand synthesis to the enantioselection pathway". supporting information; experimental part. p. 14335 - 14347. Retrieved 2011/03/22.