9H-Carbazole, 9-[(4-methylphenyl)sulfonyl]-

Base Information

• Chemical Name: 9H-Carbazole, 9-[(4-methylphenyl)sulfonyl]-
• CAS No.: 3165-71-7
• Molecular Formula: C19H15NO2S
• Molecular Weight: 321.4
• Hs Code.: 2933990090
• Mol file: 3165-71-7.mol

Synonyms:9-(4-methylphenylsulfonyl)carbazole;9-p-toluenesulfonylcarbazole;N-(4-toluenesulfonyl)carbazole;N-(2-p-toluene)sulfonyl-9H-carbazole;N-p-toluenesulphonylcarbazole;9-(4-methylphenylsulfonyl)-9H-carbazole;

Chemical Property of 9H-Carbazole, 9-[(4-methylphenyl)sulfonyl]-

Chemical Property:

• Melting Point: 137-138 °C
• Boiling Point: 530.8±43.0 °C(Predicted)
• PSA: 47.45000
• Density: 1.26±0.1 g/cm3(Predicted)
• LogP: 5.42070

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9H-Carbazole, 9-[(4-methylphenyl)sulfonyl]-

There total 56 articles about 9H-Carbazole, 9-[(4-methylphenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-biphenyl-2-yl-4-methylbenzenesulfonamide (24310-30-3) → 9-tosyl-9H-carbazole (3165-71-7)

Guidance literature:

With pyridine N-oxide; palladium 10% on activated carbon; oxygen; In dimethyl sulfoxide; at 120 ℃; for 6h; Sealed tube;

Reference yield: 100.0%

[1,1'-biphenyl]-2,2'-iodonium trifluoromethanesulfonate (189999-35-7) + toluene-4-sulfonamide (70-55-3) → 9-tosyl-9H-carbazole (3165-71-7)

Guidance literature:

With copper diacetate; sodium carbonate; In ethylene glycol; isopropyl alcohol; at 90 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.ejmech.2013.07.029

Reference yield: 90.0%

9H-carbazole (86-74-8,105184-46-1,97960-57-1) + p-toluenesulfonyl chloride (98-59-9) → 9-tosyl-9H-carbazole (3165-71-7)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; benzene; for 4h; Ambient temperature;

DOI:10.1016/S0040-4020(01)81085-1

upstream raw materials:

9H-carbazole

p-toluenesulfonyl chloride

potassium carbazole

N-(2-biphenylyl)-N-hydroxy-4-toluenesulfonamide

Downstream raw materials:

3-Bromo-9-tosyl-9H-carbazole

N-(p-toluenesulfonyl)-3-nitrocarbazole

N-(p-toluenesulfonyl)-1-nitrocarbazole

2-nitrocarbazole

Refernces

• 1、 Bai, Jiaxing,Ding, Pin,Han, Lingbo,Liu, Jingjing,Luan, Xinjun. "Fine-tuning hydroxylamines as single-nitrogen sources for Pd(0)-catalyzed diamination of o-bromo(or chloro)-biaryls". . . Retrieved 2022/03/19.
• 2、 Gao, Xinlong,Lei, Aiwen,Wang, Pan,Wang, Qingqing,Zhang, Heng,Zhang, Xiaojing. "Electrochemical Palladium-Catalyzed Intramolecular C—H Amination of 2-Amidobiaryls for Synthesis of Carbazoles". supporting information. p. 143 - 148. Retrieved 2020/12/18.