Methyl (2S)-3-(1H-indol-3-YL)-2-(methylamino)propanoate

Base Information

Chemical Name:Methyl (2S)-3-(1H-indol-3-YL)-2-(methylamino)propanoate
CAS No.:32164-04-8
Molecular Formula:C13H16N2O2
Molecular Weight:232.27800
Hs Code.:
DSSTox Substance ID:DTXSID401295882
Nikkaji Number:J246.375J
Wikidata:Q104376063
Mol file:32164-04-8.mol

Synonyms:METHYL (2S)-3-(1H-INDOL-3-YL)-2-(METHYLAMINO)PROPANOATE;32164-04-8;L-Tryptophan, N-methyl-, methyl ester;N-methyltryptophan methyl ester;Tryptophan, N-methyl-, methyl ester, L-;methyl tryptophan methylester;SCHEMBL5613870;DTXSID401295882;N-Methyl-L-tryptophan methyl ester;AM9283

Suppliers and Price of Methyl (2S)-3-(1H-indol-3-YL)-2-(methylamino)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Methyl (2S)-3-(1H-indol-3-YL)-2-(methylamino)propanoate

Chemical Property:

PSA：54.12000
LogP:1.86230
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:232.121177757
Heavy Atom Count:17
Complexity:270

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC(CC1=CNC2=CC=CC=C21)C(=O)OC
Isomeric SMILES:CN[C@@H](CC1=CNC2=CC=CC=C21)C(=O)OC

Technology Process of Methyl (2S)-3-(1H-indol-3-YL)-2-(methylamino)propanoate

There total 6 articles about Methyl (2S)-3-(1H-indol-3-YL)-2-(methylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 138119-45-6
N-phenylmethyl-N-methyl-L-tryptophan methyl ester

: 32164-04-8
(S)-(+)-N_b-methyltryptophan methyl ester

Guidance literature:: With hydrogen; palladium dihydroxide; In methanol; for 18h; under 2844.31 Torr;
DOI:10.1021/ol051441w

Reference yield: 95.0%

: 67-56-1
methanol

: 526-31-8
L-abrine

: 32164-04-8
(S)-(+)-N_b-methyltryptophan methyl ester

Guidance literature:: With thionyl chloride; at 20 ℃; for 48h;
DOI:10.1016/S0957-4166(00)00189-0

Reference yield:

: 63229-68-5
methyl N-benzyl-L-tryptophanate

: 32164-04-8
(S)-(+)-N_b-methyltryptophan methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol / 3 h / 20 °C

1.2: 563 mg / NaBH₃CN / methanol / 18 h / 20 °C

2.1: 99 percent / H₂ / Pd(OH)2 / methanol / 18 h / 2844.31 Torr

With hydrogen; palladium dihydroxide; In methanol;
DOI:10.1021/ol051441w