N-[(3Z)-3-amino-3-iminopropyl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (1:1)

Base Information

Chemical Name:N-[(3Z)-3-amino-3-iminopropyl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (1:1)
CAS No.:23999-79-3
Molecular Formula:C₁₀H₁₅N₅O₂*ClH
Molecular Weight:273.722
Hs Code.:

Synonyms:1H-Pyrrole-2-carboxamide,N-(3-amino-3-iminopropyl)-4-(formylamino)-1-methyl-, monohydrochloride (9CI);Pyrrole-2-carboxamide, N-(2-amidinoethyl)-4-formamido-1-methyl-,monohydrochloride (8CI); Distamycin 1

Suppliers and Price of N-[(3Z)-3-amino-3-iminopropyl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(3Z)-3-amino-3-iminopropyl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (1:1)

Chemical Property:

Vapor Pressure:7.78E-13mmHg at 25°C
Boiling Point:559.5°C at 760 mmHg
Flash Point:292.1°C

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[(3Z)-3-amino-3-iminopropyl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (1:1)

There total 3 articles about N-[(3Z)-3-amino-3-iminopropyl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.7%

: 78395-16-1
N-methyl-4-amino pyrrole-2-carboxamido-β-propionamidine hydrochloride

: 14901-20-3
guanidineacetic acid hydrochloride

: 538-75-0
dicyclohexyl-carbodiimide

: 23999-79-3
N-methyl-4-formamidopyrrole-2-carboxamido-β-propionamidine hydrochloride

: 78395-17-2
N-Methyl-4-(N'N'-dicyclohexylguanilyl)pyrrole-2-carboxamido-β-propionamidine Hydrochloride

Guidance literature:: In N,N-dimethyl-formamide; for 8.1h; 1) 0 deg C, 1 h, 2) r.t., overnight;
DOI:10.1002/jhet.5570170834

Reference yield:

: 24064-13-9
N-(3-amino-3-iminopropyl)-1-methyl-4-nitro-1H-pyrrole-2-carboxamide hydrochloride

: 23999-79-3
N-methyl-4-formamidopyrrole-2-carboxamido-β-propionamidine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd on charcoal / dimethylformamide

2: dimethylformamide / 1) 0 deg C, 1 h, 2) r.t., overnight

With hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570170834

Reference yield:

: 64-18-6
formic acid

: 78395-16-1
N-methyl-4-amino pyrrole-2-carboxamido-β-propionamidine hydrochloride

: 538-75-0
dicyclohexyl-carbodiimide

: 23999-79-3
N-methyl-4-formamidopyrrole-2-carboxamido-β-propionamidine hydrochloride

: 78395-17-2
N-Methyl-4-(N'N'-dicyclohexylguanilyl)pyrrole-2-carboxamido-β-propionamidine Hydrochloride

Guidance literature:: In N,N-dimethyl-formamide; Yield given. Yields of byproduct given; 1) 0 deg C, 1 h, 2) r.t., overnight;
DOI:10.1002/jhet.5570170834