Technology Process of Benzene, 1-(1,3-butadienyl)-4-chloro-, (E)-
There total 37 articles about Benzene, 1-(1,3-butadienyl)-4-chloro-, (E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
allyltriphenylphosphonium bromide;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 1h;
Inert atmosphere;
N-(p-chlorobenzylidene)-p-toluenesulfonamide;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
for 12h;
optical yield given as %de;
stereoselective reaction;
Inert atmosphere;
DOI:10.1021/ja910238f
- Guidance literature:
-
With
potassium tert-butylate;
In
tetrahydrofuran;
at 20 ℃;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/acs.orglett.9b00531
- Guidance literature:
-
methylphosphonium bromide;
With
potassium tert-butylate;
In
tetrahydrofuran;
at 20 ℃;
for 0.5h;
Inert atmosphere;
Schlenk technique;
(E)-4-chlorocinnamic aldehyde;
In
tetrahydrofuran;
at 20 ℃;
for 16.1667h;
Inert atmosphere;
Schlenk technique;
DOI:10.1039/C8CC06153J
