(E)-4-Fluoroazobenzene

Base Information

• Chemical Name: (E)-4-Fluoroazobenzene
• CAS No.: 332-00-3
• Molecular Formula: C12H9FN2
• Molecular Weight: 200.215
• Mol file: 332-00-3.mol

Synonyms:(E)-(4-fluoro-phenyl)-phenyl-diazene;(E)-(4-Fluor-phenyl)-phenyl-diazen;(4-Fluoro-phenyl)-phenyl-diazene;(E)-4-fluoroazobenzene;4-fluoroazobenzene;4-Fluor-trans-azobenzol;

Chemical Property of (E)-4-Fluoroazobenzene

Chemical Property:

• Melting Point: 68 °C
• Boiling Point: 304.1±25.0 °C(Predicted)
• PSA: 24.72000
• Density: 1.10±0.1 g/cm3(Predicted)
• LogP: 4.24110

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-4-Fluoroazobenzene

There total 13 articles about (E)-4-Fluoroazobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-(4-fluorophenyl)-2-phenylhydrazine (51789-21-0) → (E)-1-(4-fluorophenyl)-2-phenyldiazene (332-00-3)

Guidance literature:

With sodium acetate; In ethanol; at 20 ℃; Electrolysis; Green chemistry;

DOI:10.1039/c9gc00515c

Reference yield: 94.0%

(E)-4-(phenyldiazenyl)phenyl trifluoromethanesulfonate → (E)-1-(4-fluorophenyl)-2-phenyldiazene (332-00-3)

Guidance literature:

With C₅₉H₇₁F₇OPPd⁽¹⁺⁾*CF₃O₃S^(1-); cesium fluoride; In cyclohexane; at 90 ℃; for 18h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.7b01082

Reference yield: 75.0%

aniline (62-53-3) + 4-fluoroaniline (371-40-4) → (E)-1-(4-fluorophenyl)-2-phenyldiazene (332-00-3)

Guidance literature:

With dihydrogen peroxide; sodium thiosulfate; In methanol; at 60 ℃; for 24h;

DOI:10.1002/anie.202013940

upstream raw materials:

ethanol

(Z)-(4-fluoro-phenyl)-phenyl-diazene

4-fluoro-nitrosobenzene

aniline

Downstream raw materials:

(Z)-(4-fluoro-phenyl)-phenyl-diazene

Refernces

• 1、 Han, Sheng,Cheng, Ying,Liu, Shanshan,Tao, Chaofu,Wang, Aiping,Wei, Wanguo,Yu, Han,Wei, Yongge. "Selective Oxidation of Anilines to Azobenzenes and Azoxybenzenes by a Molecular Mo Oxide Catalyst". supporting information. p. 6382 - 6385. Retrieved 2021/02/09.
• 2、 Du, Ke-Si,Huang, Jing-Mei. "Electrochemical dehydrogenation of hydrazines to azo compounds". supporting information. p. 1680 - 1685. Retrieved 2019/04/08.