1,2-Bis(2-methoxyethoxy)benzene

Base Information

• Chemical Name: 1,2-Bis(2-methoxyethoxy)benzene
• CAS No.: 33332-53-5
• Molecular Formula: C12H18O4
• Molecular Weight: 226.273
• DSSTox Substance ID: DTXSID90876958
• Nikkaji Number: J1.584.340C
• Wikidata: Q82858708
• Mol file: 33332-53-5.mol

Synonyms:1,2-bis(2-methoxyethoxy)benzene;33332-53-5;SCHEMBL2974587;DTXSID90876958;SREJCFAYUPEEGI-UHFFFAOYSA-N;1,2-BIS(2-MEO-ETO)BENZENE

Chemical Property of 1,2-Bis(2-methoxyethoxy)benzene

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 226.12050905
• Heavy Atom Count: 16
• Complexity: 145

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COCCOC1=CC=CC=C1OCCOC

Technology Process of 1,2-Bis(2-methoxyethoxy)benzene

There total 3 articles about 1,2-Bis(2-methoxyethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-chloroethyl methyl ether (627-42-9) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 3,4-bis-(2-methoxyethoxy)benzene (33332-53-5)

Guidance literature:

With potassium carbonate; potassium iodide; at 85 ℃; for 4h;

Reference yield: 92.0%

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) + 2-Bromoethyl methyl ether (6482-24-2) → 3,4-bis-(2-methoxyethoxy)benzene (33332-53-5)

Guidance literature:

With caesium carbonate;

DOI:10.1021/jp960504c

Reference yield:

→ 3,4-bis-(2-methoxyethoxy)benzene (33332-53-5)

Guidance literature:

upstream raw materials:

2-chloroethyl methyl ether

benzene-1,2-diol

2-Bromoethyl methyl ether

Downstream raw materials:

1,2-bis (2-methoxyethoxy)-4-nitrobenzene

1,2-bis(2-methoxyethoxy)-4,5-dinitrobenzene

4,5-bis(2-methoxyethoxy)benzene-1,2-diamine