2-Methyl-4-(4-nitrophenyl)but-3-yn-2-ol

Base Information

Chemical Name:2-Methyl-4-(4-nitrophenyl)but-3-yn-2-ol
CAS No.:33432-53-0
Molecular Formula:C11H11NO3
Molecular Weight:205.213
Hs Code.:
DSSTox Substance ID:DTXSID10400799
Nikkaji Number:J1.522.646C
Wikidata:Q82203819

Synonyms:2-methyl-4-(4-nitrophenyl)but-3-yn-2-ol;33432-53-0;3-Butyn-2-ol, 2-methyl-4-(4-nitrophenyl)-;SCHEMBL7911029;DTXSID10400799;AKOS004118046;1-(4-Nitrophenyl)-3-methyl-1-butyne-3-ol

Suppliers and Price of 2-Methyl-4-(4-nitrophenyl)but-3-yn-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Methyl-4-(4-nitrophenyl)but-3-yn-2-ol

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:297

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C#CC1=CC=C(C=C1)[N+](=O)[O-])O

Technology Process of 2-Methyl-4-(4-nitrophenyl)but-3-yn-2-ol

There total 5 articles about 2-Methyl-4-(4-nitrophenyl)but-3-yn-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 115-19-5
2-methyl-but-3-yn-2-ol

: 586-78-7
para-nitrophenyl bromide

: 33432-53-0
2-methyl-4-(4-nitrophenyl)but-3-yn-2-ol

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; for 12h; Inert atmosphere; Reflux;
DOI:10.1002/chem.201705968

Reference yield: 97.0%

: 636-98-6
p-nitrobenzene iodide

: 115-19-5
2-methyl-but-3-yn-2-ol

: 33432-53-0
2-methyl-4-(4-nitrophenyl)but-3-yn-2-ol

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; triethylamine; copper(l) chloride; at 80 ℃;
DOI:10.1080/15421400902950030

Reference yield:

: 100-00-5
4-chlorobenzonitrile

: 115-19-5
2-methyl-but-3-yn-2-ol

: 33432-53-0
2-methyl-4-(4-nitrophenyl)but-3-yn-2-ol

Guidance literature:: With para-chlorotoluene; potassium carbonate; palladium dichloride; XPhos; In acetonitrile; at 110 ℃; for 5h; Inert atmosphere; Green chemistry;
DOI:10.1039/c4ra02720e