2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole

Base Information

Chemical Name:2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole
CAS No.:33469-37-3
Molecular Formula:C11H9F3N2O
Molecular Weight:242.2
Hs Code.:
DSSTox Substance ID:DTXSID801220899
Mol file:33469-37-3.mol

Synonyms:33469-37-3;2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole;2-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-imidazole;1H-Imidazole, 2-(4-methoxyphenyl)-5-(trifluoromethyl)-;2-(4-methoxyphenyl)-4-(trifluoromethyl)-imidazole;Imidazole, 2-[4-methoxyphenyl]-4-trifluoromethyl-;SCHEMBL7473415;SCHEMBL23847030;DTXSID801220899;AKOS015905617;AKOS025399383;FT-0761117;A18662;2-(p-methoxyphenyl)-4-(trifluoromethyl)-imidazole;A1-35059;2-(4-methoxyphenyl)-4-(trifluormethyl)-1H-imidazol;2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole #

Suppliers and Price of 2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole

Chemical Property:

Melting Point:201-203 °C
Boiling Point:372.6±42.0 °C(Predicted)
PKA:10.96±0.10(Predicted)
PSA：37.91000
Density:1.317±0.06 g/cm3(Predicted)
LogP:3.10410
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:242.06669740
Heavy Atom Count:17
Complexity:252

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC=C(N2)C(F)(F)F

Technology Process of 2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole

There total 6 articles about 2-(4-Methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 2314-97-8,263005-66-9
iodotrifluoromethane

: 52091-37-9
2-[4-(methyloxy)phenyl]-1H-imidazole

: 33469-37-3
2-(4-methoxyphenyl)-4-(trifluoromethyl)-imidazole

Guidance literature:: With triethylamine; In methanol; for 72h; Irradiation;
DOI:10.1021/jo00180a021

Reference yield: 51.0%

: 123-11-5
4-methoxy-benzaldehyde

: 431-67-4
1,1-dibromo-3,3,3-trifluoroacetone

: 33469-37-3
2-(4-methoxyphenyl)-4-(trifluoromethyl)-imidazole

Guidance literature:: 1,1-dibromo-3,3,3-trifluoroacetone; With sodium acetate; for 0.5h; Heating;

4-methoxy-benzaldehyde; With ammonium hydroxide; In methanol; at 20 ℃; for 20h;
DOI:10.1021/jm991154w