Phenol, 4-methoxy-2,6-dinitro-

Base Information

• Chemical Name: Phenol, 4-methoxy-2,6-dinitro-
• CAS No.: 3410-94-4
• Molecular Formula: C7H6N2O6
• Molecular Weight: 214.134
• DSSTox Substance ID: DTXSID00456200
• Nikkaji Number: J1.952.650J
• Wikidata: Q82278448
• Mol file: 3410-94-4.mol

Synonyms:2,6-dinitro-4-methoxyphenol;4-methoxy-2,6-dinitro-phenol;Phenol, 4-methoxy-2,6-dinitro-;3410-94-4;SCHEMBL2402093;DTXSID00456200

Chemical Property of Phenol, 4-methoxy-2,6-dinitro-

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 214.02258592
• Heavy Atom Count: 15
• Complexity: 235

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C(=C1)[N+](=O)[O-])O)[N+](=O)[O-]

Technology Process of Phenol, 4-methoxy-2,6-dinitro-

There total 13 articles about Phenol, 4-methoxy-2,6-dinitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-methoxy-phenol (150-76-5) → 4-methoxy-2,6-dinitrophenol (3410-94-4)

Guidance literature:

With trichloroisocyanuric acid; silica gel; sodium nitrite; at 20 ℃; for 0.25h;

DOI:10.1055/s-2003-42063

Reference yield: 88.0%

5-methoxysalicylic acid (2612-02-4) → 4-methoxy-2,6-dinitrophenol (3410-94-4)

Guidance literature:

With nitric acid; acetic acid; In water; at 15 ℃; for 1h;

DOI:10.1002/chem.201102732

Reference yield: 63.0%

4-methoxy-phenol (150-76-5) → 4-methoxy-2-nitrophenol (1568-70-3) + 4-methoxy-2,6-dinitrophenol (3410-94-4)

Guidance literature:

With Eu-Mo-modified montmorillonite HKSF; nitric acid; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1016/j.tet.2005.09.027

upstream raw materials:

4-methoxy-N-methyl-2,6,N-trinitro-aniline

p-tert-butoxyanisole

4-methoxy-phenol

2,6-dinitrohydroquinone

Downstream raw materials:

1,4-dimethoxy-2,6-dinitrobenzene

N-[(5,8-dimethoxy-7-nitroquinolin-2-yl)ethynyl]-N-[2-(prop-1-ynyl)phenyl]-p-toluenesulfonamide

methyl 1-(5,8-dimethoxy-7-nitroquinolin-2-yl)-4-methyl-9-tosyl-β-carboline-3-carboxylate

methyl 4-(5,8-dimethoxy-7-nitroquinolin-2-yl)-1-methyl-5-tosyl-γ-carboline-3-carboxylate