2-Cyclohexen-1-ol, (1R)-

Base Information

• Chemical Name: 2-Cyclohexen-1-ol, (1R)-
• CAS No.: 3413-44-3
• Molecular Formula: C6H10O
• Molecular Weight: 98.1448
• European Community (EC) Number: 841-373-7
• DSSTox Substance ID: DTXSID80440607
• Nikkaji Number: J582.165G
• Wikidata: Q82256962
• Mol file: 3413-44-3.mol

Synonyms:(1R)-cyclohex-2-en-1-ol;3413-44-3;2-Cyclohexen-1-ol, (1R)-;(R)-2-Cyclohexen-1-ol;r-2-cyclohexen-1-ol;(1R)-2-Cyclohexen-1-ol;DTXSID80440607;CS-0263308;EN300-86118

Chemical Property of 2-Cyclohexen-1-ol, (1R)-

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 98.073164938
• Heavy Atom Count: 7
• Complexity: 76.2

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC=CC(C1)O
• Isomeric SMILES: C1CC=C[C@@H](C1)O

Technology Process of 2-Cyclohexen-1-ol, (1R)-

There total 63 articles about 2-Cyclohexen-1-ol, (1R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

cyclohexene (110-83-8) → (R)-2-cyclohexen-1-ol (3413-44-3) + (S)-cyclohex-2-en-1-ol (6426-26-2) + cyclohexane-1,2-epoxide (286-20-4)

Guidance literature:

With oxygen; isobutyraldehyde; In acetonitrile; at 25 ℃; for 8h; Reagent/catalyst; enantioselective reaction;

DOI:10.1039/c6nj00808a

Reference yield: 69.0%

2-(Toluene-4-sulfinyl)-cyclohexanol (104792-01-0) → (R)-2-cyclohexen-1-ol (3413-44-3) + (S)-cyclohex-2-en-1-ol (6426-26-2)

Guidance literature:

With calcium carbonate; at 150 ℃; for 3h; under 10 Torr; Title compound not separated from byproducts;

DOI:10.1246/bcsj.61.1213

Reference yield: 58.0%

cyclohexenone (930-68-7) → (R)-2-cyclohexen-1-ol (3413-44-3) + (S)-cyclohex-2-en-1-ol (6426-26-2)

Guidance literature:

With lithium aluminium tetrahydride; Quinine; In diethyl ether; at 0 ℃; for 1h; Title compound not separated from byproducts;

DOI:10.1021/jo01289a031

upstream raw materials:

cyclohexene oxide

cyclohexenone

Cyclohex-2-enol

cyclohexane-1,2-epoxide

Downstream raw materials:

cyclohex-2-enyl-N-benzoylbenzimidate

2,3-epoxycyclohexanol

cis-2,3-epoxycyclohexanol

ethyl (R)-2-cyclohexenylacetate