2-[(E)-2-phenylethenyl]-1H-benzimidazole

Base Information

• Chemical Name: 2-[(E)-2-phenylethenyl]-1H-benzimidazole
• CAS No.: 1456-19-5
• Molecular Formula: C15H12 N2
• Molecular Weight: 220.274
• NSC Number: 52092
• Nikkaji Number: J1.052.004E,J2.285.867J
• ChEMBL ID: CHEMBL473721
• Mol file: 1456-19-5.mol

Synonyms:2-[(E)-2-phenylethenyl]-1H-benzimidazole;58758-09-1;1456-19-5;(E)-2-styryl-1H-benzo[d]imidazole;2-[(E)-2-phenylvinyl]-1H-benzimidazole;2-Styryl-1H-benzoimidazole;NSC52092;CL-132115;2-styrylbenzimidazole;2-(Styryl)-benzimidazole;Benzimidazole derivative, 4;MLS000551149;SCHEMBL537904;SCHEMBL537905;CHEMBL473721;(E)-2-styryl-1H-benzimidazole;2-styryl-1H-1,3-benzimidazole;BDBM85263;(E)-2-Styryl-1H-benzoimidazole;QQLPPRIZUPEKMV-ZHACJKMWSA-N;HMS2403B05;2-[(E)-styryl]-1H-benzimidazole;MFCD00160018;NSC-52092;STK871091;AKOS000275128;12H-517S;SMR000177136;BB 0219550;F15392;2-[(E)-2-phenylethenyl]-1H-1,3-benzodiazole;SR-01000499042;SR-01000499042-1;Z46024761;F0783-0066

Chemical Property of 2-[(E)-2-phenylethenyl]-1H-benzimidazole

Chemical Property:

• Vapor Pressure: 3.67E-08mmHg at 25°C
• Boiling Point: 446.3°C at 760 mmHg
• Flash Point: 242.5°C
• Density: 1.235g/cm³
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 220.100048391
• Heavy Atom Count: 17
• Complexity: 268

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CC2=NC3=CC=CC=C3N2
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/C2=NC3=CC=CC=C3N2

Technology Process of 2-[(E)-2-phenylethenyl]-1H-benzimidazole

There total 16 articles about 2-[(E)-2-phenylethenyl]-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-phenyl-propenal (104-55-2) + 1,2-diamino-benzene (95-54-5) → 2-styryl-1H-benzo[d]imidazole (1456-19-5)

Guidance literature:

With sulfonated rice husk ash; at 80 ℃; for 0.25h; Green chemistry;

DOI:10.1007/s11164-015-2075-5

Reference yield: 97.0%

2-Methyl-1H-benzimidazole (615-15-6) + benzaldehyde (100-52-7) → 2-styryl-1H-benzo[d]imidazole (1456-19-5)

Guidance literature:

With acetic anhydride; for 0.0333333h; microwave irradiation;

DOI:10.1081/SCC-120038508

Reference yield: 90.0%

cinnamaldoxime (13372-81-1) + 1,2-diamino-benzene (95-54-5) → 2-styryl-1H-benzo[d]imidazole (1456-19-5)

Guidance literature:

With 1,1'-disulfo-[2,2'-bipyridine]-1,1'-diium chloride; In ethanol; at 20 ℃; for 2h;

DOI:10.1007/s11164-014-1852-x

upstream raw materials:

Cinnamic acid

1,2-diamino-benzene

2-Methyl-1H-benzimidazole

benzaldehyde

Downstream raw materials:

1-benzyl-2-styryl-1H-benzimidazole

1-((piperidin-1-yl) methyl)-2-styryl-benzimidazole

1-((morpholino) methyl)-2-styryl-benzimidazole

1-((diethylamino) methyl)-2-styryl-benzimidazole