1-Phenyl-3-(pyridin-2-yl)prop-2-en-1-one

Base Information

Chemical Name:1-Phenyl-3-(pyridin-2-yl)prop-2-en-1-one
CAS No.:5325-66-6
Molecular Formula:C₁₄H₁₁NO
Molecular Weight:209.247
Hs Code.:
NSC Number:799,197
Nikkaji Number:J1.832.858E,J713.354E
ChEMBL ID:CHEMBL16947

Synonyms:CHEMBL16947;1-phenyl-3-(pyridin-2-yl)prop-2-en-1-one;1-phenyl-3-pyridin-2-ylprop-2-en-1-one;WR-190433;5325-66-6;MLS002637493;NSC799;3-(2-PYRIDYL)-ACRYLOPHENONE;SCHEMBL977482;NSC197;SCHEMBL6180067;beta-(2-Pyridinyl)acrylophenone;NSC-197;NSC-799;3-(2-PYRIDYL)ACRYLOPHENONE;BDBM50194663;(alphaE)-beta-(2-Pyridyl)acrylophenone;(E)-1-Phenyl-3-pyridin-2-yl-propenone

Suppliers and Price of 1-Phenyl-3-(pyridin-2-yl)prop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-Phenyl-3-(pyridin-2-yl)prop-2-en-1-one

Chemical Property:

Vapor Pressure:2.16E-05mmHg at 25°C
Boiling Point:360.9°C at 760 mmHg
Flash Point:179.8°C
Density:1.143g/cm³
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:209.084063974
Heavy Atom Count:16
Complexity:254

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C=CC2=CC=CC=N2
Isomeric SMILES:C1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=N2

Technology Process of 1-Phenyl-3-(pyridin-2-yl)prop-2-en-1-one

There total 2 articles about 1-Phenyl-3-(pyridin-2-yl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1121-60-4
pyridine-2-carbaldehyde

: 98-86-2
acetophenone

: 5325-66-6,20890-12-4,72491-18-0
1-phenyl-3-(2-pyridyl)propen-1-one

Guidance literature:: With calcined tungstophosphoric acid; In neat (no solvent); at 20 ℃; for 1.25h; Reagent/catalyst;
DOI:10.14233/ajchem.2019.22219

Reference yield: 88.0%

: 5325-66-6,20890-12-4,72491-18-0
1-phenyl-3-(2-pyridyl)propen-1-one

Guidance literature:: With potassium hydroxide; In ethanol; at 20 ℃; for 2h;

Reference yield: 99.0%

: 5325-66-6,20890-12-4,72491-18-0
1-phenyl-3-(2-pyridyl)propen-1-one

: 67492-50-6
(3,5-dichlorophenyl)boronic acid

: (S)-3-(3,5-dichlorophenyl)-1-phenyl-3-(pyridin-2-yl)propan-1-one

Guidance literature:: With (R)-(+)-(4,4'-bi-1,3-benzodioxole)-5,5'-diylbis(di(3,5-dimethylphenyl)phosphine); di-μ-chloro-bis[bis(cyclo-octene)rhodium]; potassium hydroxide; In tetrahydrofuran; water; at 80 ℃; for 12h; enantioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1002/adsc.202000211