1-(Diphenylphosphoryl)-2-methylpropan-2-ol

Base Information

Chemical Name:1-(Diphenylphosphoryl)-2-methylpropan-2-ol
CAS No.:35078-75-2
Molecular Formula:C16H19O2P
Molecular Weight:274.299
Hs Code.:
DSSTox Substance ID:DTXSID10516480
Wikidata:Q82377924
Mol file:35078-75-2.mol

Synonyms:35078-75-2;1-(Diphenylphosphoryl)-2-methylpropan-2-ol;DTXSID10516480

Suppliers and Price of 1-(Diphenylphosphoryl)-2-methylpropan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(Diphenylphosphoryl)-2-methylpropan-2-ol

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:274.11226684
Heavy Atom Count:19
Complexity:304

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(CP(=O)(C1=CC=CC=C1)C2=CC=CC=C2)O

Technology Process of 1-(Diphenylphosphoryl)-2-methylpropan-2-ol

There total 5 articles about 1-(Diphenylphosphoryl)-2-methylpropan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 67-64-1
acetone

: 2129-89-7
diphenyl(methyl)phosphine oxide

: 35078-75-2
(2-hydroxy-2-methylpropyl)diphenylphosphine oxide

Guidance literature:: diphenyl(methyl)phosphine oxide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.833333h; Inert atmosphere; Schlenk technique;

acetone; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h; Inert atmosphere; Schlenk technique;
DOI:10.1016/j.tet.2016.06.070

Reference yield: 72.5%

: 1733-52-4
1-(diphenylphosphinoyl)propan-2-one

: 917-54-4
methyllithium

: 35078-75-2
(2-hydroxy-2-methylpropyl)diphenylphosphine oxide

Guidance literature:: With cerium(III) chloride; In tetrahydrofuran; -78 degC, 1 h, then allowed to warm to 0 degC very slowly;
DOI:10.1016/S0040-4039(00)74431-5