5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one

Base Information

Chemical Name:5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one
CAS No.:35978-37-1
Molecular Formula:C12H7FN2OS
Molecular Weight:246.265
Hs Code.:2934999090
European Community (EC) Number:674-822-9
DSSTox Substance ID:DTXSID50352480
Wikidata:Q82129649
ChEMBL ID:CHEMBL1532322
Mol file:35978-37-1.mol

Synonyms:35978-37-1;5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one;5-(4-fluorophenyl)-3H-thieno[2,3-d]pyrimidin-4-one;5-(4-fluorophenyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one;5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-ol;MFCD00297812;Thieno[2,3-d]pyrimidin-4(1H)-one, 5-(4-fluorophenyl)-;5-(4-Fluoro-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one;MLS000099304;IFLab1_003186;SCHEMBL2368426;CHEMBL1532322;DTXSID50352480;HMS1421A18;HMS2376J14;STK108905;STK842115;AKOS000272798;AKOS005625449;AKOS028109441;CCG-274152;FS-1652;NCGC00061891-02;SMR000071449;CS-0307738;FT-0688004;EN300-06071;F81406;AB00296086-11;SR-01000246743;J-516245;SR-01000246743-1;Z56801645

Suppliers and Price of 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-(4-Fluorophenyl)-3H-thieno[2,3-d]pyrimidin-4-one
1 g
$ 225.00

SynQuest Laboratories
5-(4-Fluorophenyl)-3H-thieno[2,3-d]pyrimidin-4-one
250 mg
$ 105.00

Matrix Scientific
5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one
10g
$ 1361.00

Matrix Scientific
5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one
5g
$ 882.00

Matrix Scientific
5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one
1g
$ 286.00

Frontier Specialty Chemicals
5-(4-Fluorophenyl)-3H-thieno[2,3-d]pyrimidin-4-one 97%
250mg
$ 85.00

Frontier Specialty Chemicals
5-(4-Fluorophenyl)-3H-thieno[2,3-d]pyrimidin-4-one 97%
1g
$ 281.00

Crysdot
5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one 95+%
5g
$ 387.00

Chemenu
5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one 95%
5g
$ 362.00

Apolloscientific
5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one
5g
$ 448.00

Total 13 raw suppliers

Chemical Property of 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one

Chemical Property:

Melting Point:222°C
PSA：73.99000
LogP:2.79070
Storage Temp.:2-8°C
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:246.02631219
Heavy Atom Count:17
Complexity:341

Purity/Quality:

99%, ^*data from raw suppliers

5-(4-Fluorophenyl)-3H-thieno[2,3-d]pyrimidin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CSC3=C2C(=O)NC=N3)F

Technology Process of 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one

There total 6 articles about 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.8%

: 64-18-6
formic acid

: 519016-84-3
2-amino-4-(4-fluorophenyl)thiophene-3-carbonitrile

: 35978-37-1
5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one

Guidance literature:: With acetic anhydride; at 110 ℃; for 36h; Inert atmosphere;
DOI:10.1016/j.bmc.2011.05.038

Reference yield:

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 35978-33-7
ethyl 2-amino-4-(4-fluorophenyl)-thiophene-3-carboxylate

: 35978-37-1
5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one

Guidance literature:: at 200 ℃;

Reference yield:

: 403-42-9
1-(4-fluorophenyl)ethanone

: 35978-37-1
5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sulfur; triethylamine / diethyl ether / 12 h / 20 °C

2: 24 h / 160 - 170 °C

With sulfur; triethylamine; In diethyl ether;
DOI:10.1016/j.ejmech.2010.12.025