2-Amino-1-(4-phenylpiperazin-1-yl)ethan-1-one

Base Information

Chemical Name:2-Amino-1-(4-phenylpiperazin-1-yl)ethan-1-one
CAS No.:359821-44-6
Molecular Formula:C12H17N3O
Molecular Weight:219.286
Hs Code.:
European Community (EC) Number:836-606-4
DSSTox Substance ID:DTXSID001268231
Mol file:359821-44-6.mol

Synonyms:2-amino-1-(4-phenylpiperazin-1-yl)ethan-1-one;359821-44-6;2-amino-1-(4-phenylpiperazin-1-yl)ethanone;SCHEMBL8245954;DTXSID001268231;BBL011242;MFCD06742064;STK937096;AKOS000174912;2-Amino-1-(4-phenyl-1-piperazinyl)ethanone;CS-0252052;EN300-58642;Z65027923

Suppliers and Price of 2-Amino-1-(4-phenylpiperazin-1-yl)ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Amino-1-(4-phenylpiperazin-1-yl)ethan-1-one

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:219.137162174
Heavy Atom Count:16
Complexity:230

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1C2=CC=CC=C2)C(=O)CN

Technology Process of 2-Amino-1-(4-phenylpiperazin-1-yl)ethan-1-one

There total 4 articles about 2-Amino-1-(4-phenylpiperazin-1-yl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 946523-05-3
benzyl ester of [2-(4-phenylpiperazin-1-yl)-2-oxoethyl]carbamic acid

: 359821-44-6
glycine-4-phenylpiperazin-1-ylamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 3h; under 2585.81 Torr;
DOI:10.1021/jm070443e

Reference yield:

: 92-54-6
4-phenyl-1-piperazine

: 359821-44-6
glycine-4-phenylpiperazin-1-ylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-hydroxybenzotriazole / dimethylformamide / 17 h / 20 °C

2: H₂ / Pd/C / ethanol / 3 h / 2585.81 Torr

With hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm070443e