4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone

Base Information

Chemical Name:4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone
CAS No.:36159-73-6
Molecular Formula:C16H13ClO
Molecular Weight:256.72700
Hs Code.:
Mol file:36159-73-6.mol

Synonyms:4-p-Chlorphenyl-1-tetralon;4-(4-chlorophenyl)-1,2,3,4-tetrahydronaphth-1-one;4-(4-chlorophenyl)-3,4-dihydronaphthalen-1(2H)-one;

Suppliers and Price of 4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone
1g
$ 950.00

Medical Isotopes, Inc.
4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone
100 mg
$ 290.00

Total 5 raw suppliers

Chemical Property of 4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone

Chemical Property:

PSA：17.07000
LogP:4.44840
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Intermediate in the preparation of Sertraline (S280000) and its derivatives.

Technology Process of 4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone

There total 10 articles about 4-(4-Chlorophenyl)-3,4-dihydro-1(2H)-naphthalenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

: 90-15-3
α-naphthol

: 108-90-7
chlorobenzene

: 36159-73-6
4-(p-chlorophenyl)-1-tetralone

: 82101-36-8
4-(o-chlorophenyl)-1-tetralone

Guidance literature:: With aluminum tri-bromide; at 22 ℃; for 24h;

Reference yield:

: 18410-18-9
γ-(4-chlorophenyl)-γ-butyrolactone

: 71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1
benzene

: 36159-73-6
4-(p-chlorophenyl)-1-tetralone

Guidance literature:: With trifluorormethanesulfonic acid; at 60 ℃; for 2h;

Reference yield:

: 99-91-2
para-chloroacetophenone

: 36159-73-6
4-(p-chlorophenyl)-1-tetralone

Guidance literature:: Multi-step reaction with 5 steps

1.1: acetic acid / Reflux

2.1: acetic acid; zinc / water / 20 °C

3.1: sodium hydroxide / water / 80 °C / pH 11

3.2: 4 h

4.1: hydrogenchloride / water / 3 h / pH 1 - 2

5.1: trifluorormethanesulfonic acid / 2 h / 60 °C

With hydrogenchloride; trifluorormethanesulfonic acid; acetic acid; sodium hydroxide; zinc; In water;