4-Benzyloxystyrene

Base Information

• Chemical Name: 4-Benzyloxystyrene
• CAS No.: 36438-64-9
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• European Community (EC) Number: 844-375-6
• DSSTox Substance ID: DTXSID80453459
• Nikkaji Number: J798.578I
• Wikidata: Q82274605
• Mol file: 36438-64-9.mol

Synonyms:4-Benzyloxystyrene;36438-64-9;1-(BENZYLOXY)-4-ETHENYLBENZENE;1-Ethenyl-4-phenylmethoxybenzene;p-benzyloxy styrene;4-(Benzyloxy)styrene;1-Benzyloxy-4-vinyl-benzene;SCHEMBL763259;DTXSID80453459;KZZFTQRVWYBBNL-UHFFFAOYSA-N;AKOS013993812;CS-0236157;EN300-1694013;A1-05198

Chemical Property of 4-Benzyloxystyrene

Chemical Property:

• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 198

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC1=CC=C(C=C1)OCC2=CC=CC=C2

Technology Process of 4-Benzyloxystyrene

There total 24 articles about 4-Benzyloxystyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

p-benzyloxybenzaldehyde (4397-53-9) + methyl-triphenylphosphonium iodide (2065-66-9) → p-benzyloxystyrene (36438-64-9)

Guidance literature:

methyl-triphenylphosphonium iodide; With sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

p-benzyloxybenzaldehyde; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1002/ejoc.200901497

Reference yield: 96.0%

p-benzyloxybenzaldehyde (4397-53-9) → p-benzyloxystyrene (36438-64-9)

Guidance literature:

With methyl-triphenylphosphonium iodide; sodium hydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/c8cc05643a

Reference yield: 94.0%

p-benzyloxybenzaldehyde (4397-53-9) + Methyltriphenylphosphonium bromide (1779-49-3) → p-benzyloxystyrene (36438-64-9)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at -10 ℃; for 0.0833333h; Inert atmosphere;

p-benzyloxybenzaldehyde; In tetrahydrofuran; at -10 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.bmc.2020.115529

upstream raw materials:

(benzyloxy)benzene

paracetaldehyde

1-(4-[benzyloxy]phenyl)ethan-1-ol

p-benzyloxybenzaldehyde

Downstream raw materials:

(R)-2-(tert-butoxycarbonyl)amino-2-(4-benzyloxyphenyl)ethanol

2-(4-benzyloxyphenyl)ethanol

4-[2-(2,4-diamino-quinazolin-6-yl)-ethyl]-phenol