Pyrimidine-4,5-dicarboxylic acid diethyl ester

Base Information

Chemical Name:Pyrimidine-4,5-dicarboxylic acid diethyl ester
CAS No.:36978-53-7
Molecular Formula:C10H12N2O4
Molecular Weight:224.21300
Hs Code.:2933599090
European Community (EC) Number:861-186-4
ChEMBL ID:CHEMBL4533644
Mol file:36978-53-7.mol

Synonyms:36978-53-7;pyrimidine-4,5-dicarboxylic acid diethyl ester;diethyl pyrimidine-4,5-dicarboxylate;4,5-diethyl pyrimidine-4,5-dicarboxylate;SCHEMBL7844021;CHEMBL4533644;SSEHRLNTVKILCW-UHFFFAOYSA-N;AKOS033752161;AT18395;4,5-diethylpyrimidine-4,5-dicarboxylate;EN300-198993;Z1982316817

Suppliers and Price of Pyrimidine-4,5-dicarboxylic acid diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,5-diethylpyrimidine-4,5-dicarboxylate
10mg
$ 45.00

Total 1 raw suppliers

Chemical Property of Pyrimidine-4,5-dicarboxylic acid diethyl ester

Chemical Property:

PSA：78.38000
LogP:0.83000
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:224.07970687
Heavy Atom Count:16
Complexity:257

Purity/Quality:: 4,5-diethylpyrimidine-4,5-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CN=CN=C1C(=O)OCC

Technology Process of Pyrimidine-4,5-dicarboxylic acid diethyl ester

There total 2 articles about Pyrimidine-4,5-dicarboxylic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 3473-63-0
formamidine acetic acid

: 52942-64-0,55130-49-9
diethyl(ethoxymethylene)oxalacetate

: 36978-53-7
diethyl pyrimidine-4,5-dicarboxylate

Guidance literature:: In benzene; for 2.5h; Heating;
DOI:10.1002/jhet.5570300624

Reference yield:

: 108-56-5
diethyl oxaloacetate

: 36978-53-7
diethyl pyrimidine-4,5-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / acetic anhydride / 3 h / 120 - 140 °C

2: 68 percent / benzene / 2.5 h / Heating

With acetic anhydride; In benzene;
DOI:10.1002/jhet.5570300624