4-Pyridinecarboxaldehyde, 2-[[(1S)-1-phenylethyl]amino]-

Base Information

Chemical Name:4-Pyridinecarboxaldehyde, 2-[[(1S)-1-phenylethyl]amino]-
CAS No.:383426-38-8
Molecular Formula:C14H14N2O
Molecular Weight:226.278
Hs Code.:
DSSTox Substance ID:DTXSID30473561
Wikidata:Q82303047

Synonyms:383426-38-8;4-Pyridinecarboxaldehyde, 2-[[(1S)-1-phenylethyl]amino]-;SCHEMBL7242746;DTXSID30473561

Suppliers and Price of 4-Pyridinecarboxaldehyde, 2-[[(1S)-1-phenylethyl]amino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Pyridinecarboxaldehyde, 2-[[(1S)-1-phenylethyl]amino]-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:226.110613074
Heavy Atom Count:17
Complexity:238

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NC2=NC=CC(=C2)C=O
Isomeric SMILES:C[C@@H](C1=CC=CC=C1)NC2=NC=CC(=C2)C=O

Technology Process of 4-Pyridinecarboxaldehyde, 2-[[(1S)-1-phenylethyl]amino]-

There total 12 articles about 4-Pyridinecarboxaldehyde, 2-[[(1S)-1-phenylethyl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 383426-39-9
2-{[(1S)-1-phenylethyl]amino}-isonicotinonitrile

: 383426-38-8
2-{[(1S)-1-phenylethyl]amino}isonicotinaldehyde

Guidance literature:: 2-{[(1S)-1-phenylethyl]amino}-isonicotinonitrile; With diisobutylaluminium hydride; In toluene; at -15 ℃;

With hydrogenchloride;
DOI:10.1016/S0040-4039(01)01428-9

Reference yield:

: 461-87-0
2-fluoro-4-methylpyridine

: 383426-38-8
2-{[(1S)-1-phenylethyl]amino}isonicotinaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: tert.-butylnitrite; potassium tert-butylate / tetrahydrofuran

2.1: 140 °C

3.1: diisobutylaluminium hydride / toluene / -15 °C

3.2: aq. HCl

With tert.-butylnitrite; potassium tert-butylate; diisobutylaluminium hydride; In tetrahydrofuran; toluene;
DOI:10.1016/S0040-4039(01)01428-9

Reference yield:

: 383426-37-7
(2-fluoropyridin-4-yl)methan-N-hydroxyimine

: 383426-38-8
2-{[(1S)-1-phenylethyl]amino}isonicotinaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: titanium(IV) isopropylate / dimethyl sulfoxide / 110 °C

2.1: diisobutylaluminium hydride / toluene / -15 °C

2.2: aq. HCl

With titanium(IV) isopropylate; diisobutylaluminium hydride; In dimethyl sulfoxide; toluene;
DOI:10.1016/S0040-4039(01)01428-9