Bis(4-methylbenzyl) ether

Base Information

• Chemical Name: Bis(4-methylbenzyl) ether
• CAS No.: 38460-98-9
• Molecular Formula: C16H18O
• Molecular Weight: 226.318
• DSSTox Substance ID: DTXSID90493200
• Nikkaji Number: J507.633A
• Wikidata: Q82339723
• Mol file: 38460-98-9.mol

Synonyms:Bis(4-methylbenzyl) ether;p-methylbenzyl ether;38460-98-9;SCHEMBL3161372;DTXSID90493200;1,1'-[Oxybis(methylene)]bis(4-methylbenzene)

Chemical Property of Bis(4-methylbenzyl) ether

Chemical Property:

• Melting Point: 61-62 °C(Solv: hexane (110-54-3))
• Boiling Point: 324.0±11.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.020±0.06 g/cm3(Predicted)
• LogP: 4.02020
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 226.135765193
• Heavy Atom Count: 17
• Complexity: 176

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)COCC2=CC=C(C=C2)C

Technology Process of Bis(4-methylbenzyl) ether

There total 37 articles about Bis(4-methylbenzyl) ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

triethylsilane (617-86-7) + 4-methyl-benzaldehyde (104-87-0) → hexaethyl disiloxane (994-49-0) + bis(4-methylbenzyl) ether (38460-98-9)

Guidance literature:

With uranyl(VI) triflate; In dichloromethane-d2; at 20 ℃; for 2h;

DOI:10.1021/acscatal.9b01408

Reference yield: 81.0%

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 4-Methylbenzyl alcohol (589-18-4) + bis(4-methylbenzyl) ether (38460-98-9)

Guidance literature:

Nafion-H; at 90 - 95 ℃; for 1h; Title compound not separated from byproducts;

DOI:10.1021/jo00006a023

Reference yield: 74.0%

4-Methylbenzyl alcohol (589-18-4) → bis(4-methylbenzyl) ether (38460-98-9) + 4-Methylbenzyl chloride (104-82-5)

Guidance literature:

With chloro-trimethyl-silane; In neat (no solvent); at 70 - 75 ℃; for 2h; chemoselective reaction; Green chemistry;

DOI:10.1016/j.tetlet.2016.04.083

upstream raw materials:

formaldehyd

benzylmagnesium chloride

4-methyl-benzaldehyde

potassium hydrogencarbonate

Downstream raw materials:

4-methylbenzyl iodide

4-Methylbenzyl bromide

4-Methylbenzyl alcohol

4-methyl-benzaldehyde