AURORA KA-3682

Base Information

• Chemical Name: AURORA KA-3682
• CAS No.: 6933-54-6
• Molecular Formula: C₁₃H₁₅N
• Molecular Weight: 185.269
• Hs Code.: 2933990090
• Mol file: 6933-54-6.mol

Synonyms:6-methyl-5,6,7,8,9-pentahydro-4aH-carbazole;3-methyl-1,2,3,4-tetrahydrocarbazole;3-Methyl-1,2,3,4-tetrahydro-carbazol;3-methyl-2,3,4,9--tetrahydro-1H-carbazole;(3R)-3-methyl-2,3,4,9-tetrahydro-1H-carbazole;

Chemical Property of AURORA KA-3682

Chemical Property:

• Vapor Pressure: 0.000353mmHg at 25°C
• Boiling Point: 328.8°C at 760 mmHg
• Flash Point: 141.8°C
• PSA: 15.79000
• Density: 1.098g/cm³
• LogP: 3.29270

Purity/Quality:

98%min ^*data from raw suppliers

3-Methyl-2,3,4,9-tetrahydro-1H-carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of AURORA KA-3682

There total 21 articles about AURORA KA-3682 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-methylcyclohexan-4-one (589-92-4) + phenylhydrazine (100-63-0) → 3-methyl-2,3,4,9-tetrahydro-1H-carbazole (6933-54-6,100986-21-8)

Guidance literature:

With trichloroacetic acid; at 100 ℃; for 0.0833333h;

DOI:10.1515/HC.2003.9.1.9

Reference yield: 95.0%

3-methyl-1,2,3,4,4a,9a-hexahydro-carbazole (6731-87-9) → 3-methyl-2,3,4,9-tetrahydro-1H-carbazole (6933-54-6,100986-21-8)

Guidance literature:

With trimethylamine-N-oxide; Co(salophen)-HQ; In methanol; at 80 ℃; for 16h; Sealed tube; Green chemistry;

DOI:10.1002/chem.202102483

Reference yield: 92.0%

di-tert-butyl 1-(4-methylcyclohex-1-en-1-yl)-2-phenylhydrazine-1,2-dicarboxylate → 3-methyl-2,3,4,9-tetrahydro-1H-carbazole (6933-54-6,100986-21-8)

Guidance literature:

With zinc(II) chloride; In 1,4-dioxane; at 20 - 90 ℃; for 1h; regioselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1021/ol502031q

upstream raw materials:

4-methyl-cyclohexanone-phenylhydrazone

acetic acid

1-methylcyclohexan-4-one

phenylhydrazine

Downstream raw materials:

3-Methyl-9H-carbazole

9H-carbazole-3-carbaldehyde

1-methoxy-3-methylcarbazole

1-hydroxy-3-methyl-9H-carbazole