H2N-PEG6-OH

Base Information

• Chemical Name: H2N-PEG6-OH
• CAS No.: 39160-70-8
• Molecular Formula: C12H27NO6
• Molecular Weight: 281.349
• Hs Code.: 3822000000
• Mol file: 39160-70-8.mol

Synonyms:2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol;

Chemical Property of H2N-PEG6-OH

Chemical Property:

• Boiling Point: 388.0±37.0 °C(Predicted)
• PKA: 14.36±0.10(Predicted)
• PSA: 92.40000
• Density: 1.083±0.06 g/cm3(Predicted)
• LogP: -0.27930
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Soluble in Water, DMSO, DCM, DMF

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-AminohexaethyleneGlycol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Amino-PEG6-alcohol is a PEG reagent with one an amino group (NH2) and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters.
• Uses: A polyethyleneglycol (PEG) derivative, 1-AMinohexaethylene Glycol can be used in the preparation of single cell optical biosensors.

Technology Process of H2N-PEG6-OH

There total 16 articles about H2N-PEG6-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol (86770-69-6) → 3,6,9,12,15,18-hexaoxa-1-octadecyl amine (39160-70-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 5h;

Reference yield: 91.0%

{2-[2-(2-{2-[2-(2-Azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxymethyl}-benzene (86770-73-2) → 3,6,9,12,15,18-hexaoxa-1-octadecyl amine (39160-70-8)

Guidance literature:

With hydrogen; palladium;

Reference yield: 86.0%

→ 3,6,9,12,15,18-hexaoxa-1-octadecyl amine (39160-70-8)

Guidance literature:

upstream raw materials:

17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol

{2-[2-(2-{2-[2-(2-Azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxymethyl}-benzene

2-(17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl)isoindoline-1,3-dione

pentaethylene glycol

Downstream raw materials:

17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol

tert-butyl (17-(((4S)-6-(4-chlorophenyl)-4-(2-(ethylamino)-2-oxoethyl)-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-8-yl)oxy)-3,6,9,12,15-pentaoxaheptadecyl)carbamate

2-(2-(2-(2-(2-(2-t-butyloxycarbonylaminoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxyacetatic acid

benzyl N-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate