Carbamic acid, [1-(4-nitrophenyl)-4-piperidinyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [1-(4-nitrophenyl)-4-piperidinyl]-, 1,1-dimethylethyl ester
CAS No.:392335-21-6
Molecular Formula:C16H23N3O4
Molecular Weight:321.376
Hs Code.:
Mol file:392335-21-6.mol

Synonyms:t-butyl 1-(4-nitrophenyl)piperidin-4-ylcarbamate;tert-butyl (1-(4-nitrophenyl)piperidin-4-yl)carbamate;[1-(4-nitro-phenyl)-piperidin-4-yl]-carbamic acid tert-butyl ester;

Suppliers and Price of Carbamic acid, [1-(4-nitrophenyl)-4-piperidinyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Carbamic acid, [1-(4-nitrophenyl)-4-piperidinyl]-, 1,1-dimethylethyl ester

Chemical Property:

Boiling Point:494.8±45.0 °C(Predicted)
PSA：87.39000
Density:1.21±0.1 g/cm3(Predicted)
LogP:4.06740

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of Carbamic acid, [1-(4-nitrophenyl)-4-piperidinyl]-, 1,1-dimethylethyl ester

There total 2 articles about Carbamic acid, [1-(4-nitrophenyl)-4-piperidinyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.59%

: 73874-95-0
(piperidin-4-yl)carbamic acid tert-butyl ester

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 392335-21-6
tert-butyl N-[1-(4-nitrophenyl)piperidin-4-yl]carbamate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide;

Reference yield:

: 100-00-5
4-chlorobenzonitrile

: 73874-95-0
(piperidin-4-yl)carbamic acid tert-butyl ester

: 392335-21-6
tert-butyl N-[1-(4-nitrophenyl)piperidin-4-yl]carbamate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 8h;
DOI:10.1021/acs.jmedchem.6b00902

Reference yield: 97.0%

: 392335-21-6
tert-butyl N-[1-(4-nitrophenyl)piperidin-4-yl]carbamate

: 74-88-4
methyl iodide

: tert-butyl methyl(1-(4-nitrophenyl)piperidin-4-yl)carbamate

Guidance literature:: tert-butyl N-[1-(4-nitrophenyl)piperidin-4-yl]carbamate; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;