BroMo-N-(2-hydroxy-1,1-diMethylethyl)benzaMide

Base Information

Chemical Name:BroMo-N-(2-hydroxy-1,1-diMethylethyl)benzaMide
CAS No.:33708-69-9
Molecular Formula:C11H14BrNO2
Molecular Weight:272.142
Hs Code.:
Mol file:33708-69-9.mol

Synonyms:N-(1,1-dimethyl-2-hydroxyethyl)-4-bromobenzamide;4-Bromo-N-(2-hydroxy-1,1-dimethylethyl)-benzamide;2-(4-bromo-benzoylamino)-2-methyl-propan-1-ol;4-bromo-N-[2-(2-methyl-2-propan-1-ol)]benzamide;2-(p-Brombenzamido)-2-methylpropan-1-ol;Benzamide,p-bromo-N-(2-hydroxy-1,1-dimethylethyl);

Suppliers and Price of BroMo-N-(2-hydroxy-1,1-diMethylethyl)benzaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide
25mg
$ 140.00

TRC
Bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide
250mg
$ 690.00

Medical Isotopes, Inc.
Bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide
250 mg
$ 1125.00

Crysdot
4-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)benzamide 95+%
1g
$ 465.00

American Custom Chemicals Corporation
4-BROMO-N-(1-HYDROXY-2-METHYLPROPAN-2-YL)BENZAMIDE 95.00%
5MG
$ 499.31

Alichem
4-Bromo-n-(1-hydroxy-2-methylpropan-2-yl)benzamide
5g
$ 2049.84

Alichem
4-Bromo-n-(1-hydroxy-2-methylpropan-2-yl)benzamide
1g
$ 637.29

Alichem
4-Bromo-n-(1-hydroxy-2-methylpropan-2-yl)benzamide
250mg
$ 281.41

Total 8 raw suppliers

Chemical Property of BroMo-N-(2-hydroxy-1,1-diMethylethyl)benzaMide

Chemical Property:

Vapor Pressure:1.16E-07mmHg at 25°C
Boiling Point:415.9°C at 760 mmHg
Flash Point:205.3°C
PSA：49.33000
Density:1.409g/cm³
LogP:2.34070
Solubility.:Chloroform, DCM, Ethyl Acetate

Purity/Quality:

97% ^*data from raw suppliers

Bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Bromo-N-(2-hydroxy-1,1-dimethylethyl)benzamide is an intermediate in the synthesis of positional isomers and analogs of mazindol (M198500), as potential inhibitors of cocaine binding site of the dopamine transporter site.

Technology Process of BroMo-N-(2-hydroxy-1,1-diMethylethyl)benzaMide

There total 1 articles about BroMo-N-(2-hydroxy-1,1-diMethylethyl)benzaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 124-68-5
2-Amino-2-methyl-1-propanol

: 586-75-4
4-chlorobenzoyl chloride

: 33708-69-9
4-bromo-N-[2-(2-methyl-2-propan-1-ol)]benzamide

Guidance literature:: In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 33708-69-9
4-bromo-N-[2-(2-methyl-2-propan-1-ol)]benzamide

: 4-chlorophenyl-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-methanone

Guidance literature:: Multi-step reaction with 5 steps

1.1: 60 percent / thionyl chloride / toluene; CH₂Cl₂ / 72 h / 20 °C

2.1: Mg / tetrahydrofuran / 1.5 h / Heating

2.2: 53 percent / tetrahydrofuran / 2.5 h / Heating

3.1: acetonitrile; dimethylformamide / 24 h / 20 °C

4.1: 47 percent / acetonitrile / 10 h / Heating

5.1: 39 percent / MnO₂ / CH₂Cl₂; N,N-dimethyl-acetamide / 3 h / 20 °C

With manganese(IV) oxide; thionyl chloride; magnesium; In tetrahydrofuran; dichloromethane; N,N-dimethyl acetamide; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

: 33708-69-9
4-bromo-N-[2-(2-methyl-2-propan-1-ol)]benzamide

: 211388-42-0
4-chloro-α-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-benzenemethanol

Guidance literature:: Multi-step reaction with 4 steps

1.1: 60 percent / thionyl chloride / toluene; CH₂Cl₂ / 72 h / 20 °C

2.1: Mg / tetrahydrofuran / 1.5 h / Heating

2.2: 53 percent / tetrahydrofuran / 2.5 h / Heating

3.1: acetonitrile; dimethylformamide / 24 h / 20 °C

4.1: 47 percent / acetonitrile / 10 h / Heating

With thionyl chloride; magnesium; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile;