5-((Benzyloxy)methyl)-1H-pyrazol-3-amine

Base Information

Chemical Name:5-((Benzyloxy)methyl)-1H-pyrazol-3-amine
CAS No.:393590-62-0
Molecular Formula:C11H13N3O
Molecular Weight:203.24000
Hs Code.:2933199090
DSSTox Substance ID:DTXSID90447667
Wikidata:Q82266541
Mol file:393590-62-0.mol

Synonyms:393590-62-0;5-((Benzyloxy)methyl)-1H-pyrazol-3-amine;5-(benzyloxymethyl)-1H-pyrazol-3-amine;5-(phenylmethoxymethyl)-1H-pyrazol-3-amine;5-Benzyloxymethyl-2H-pyrazol-3-ylamine;SCHEMBL958531;SCHEMBL23854651;DTXSID90447667;YIBUHJHRURIGRW-UHFFFAOYSA-N;3-(benzyloxymethyl)-1H-pyrazol-5-amine;CS-0452073;FT-0686289

Suppliers and Price of 5-((Benzyloxy)methyl)-1H-pyrazol-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-(Benzyloxymethyl)-1H-pyrazol-3-amine 97%
5g
$ 1035.00

Crysdot
5-((Benzyloxy)methyl)-1H-pyrazol-3-amine 95+%
1g
$ 381.00

Chemenu
5-((benzyloxy)methyl)-1H-pyrazol-3-amine 95%
1g
$ 356.00

American Custom Chemicals Corporation
5-((BENZYLOXY)METHYL)-1H-PYRAZOL-3-AMINE 95.00%
5MG
$ 502.55

Alichem
5-((Benzyloxy)methyl)-1H-pyrazol-3-amine
1g
$ 795.76

Alichem
5-((Benzyloxy)methyl)-1H-pyrazol-3-amine
250mg
$ 347.75

AK Scientific
5-((Benzyloxy)methyl)-1H-pyrazol-3-amine
5g
$ 1973.00

Total 7 raw suppliers

Chemical Property of 5-((Benzyloxy)methyl)-1H-pyrazol-3-amine

Chemical Property:

PSA：63.93000
LogP:2.28990
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:203.105862047
Heavy Atom Count:15
Complexity:183

Purity/Quality:

98%min ^*data from raw suppliers

5-(Benzyloxymethyl)-1H-pyrazol-3-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COCC2=CC(=NN2)N

Technology Process of 5-((Benzyloxy)methyl)-1H-pyrazol-3-amine

There total 4 articles about 5-((Benzyloxy)methyl)-1H-pyrazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 32122-09-1
ethyl benzyloxyacetate

: 75-05-8,26809-02-9
acetonitrile

: 393590-62-0
5-[(benzyloxy)methyl]-1H-pyrazol-3-amine

Guidance literature:: acetonitrile; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

ethyl benzyloxyacetate; In tetrahydrofuran; hexane; at 20 ℃; for 2h;

With hydrazine hydrate; In ethanol; for 10h; Further stages.; Heating;
DOI:10.1021/jm010326y

Reference yield:

: 118602-96-3
4-benzyloxy-3-oxobutyronitrile

: 1185908-13-7,393590-62-0
5-[(phenylmethoxy)methyl]-1H-pyrazol-3-amine

Guidance literature:: With hydrazine hydrate; In ethanol; for 16h; Reflux;

Reference yield:

: 32122-09-1
ethyl benzyloxyacetate

: 1185908-13-7,393590-62-0
5-[(phenylmethoxy)methyl]-1H-pyrazol-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere

1.2: 1 h / -78 °C

2.1: hydrazine hydrate / ethanol / 16 h / Reflux

With n-butyllithium; hydrazine hydrate; In tetrahydrofuran; ethanol; hexane;