2-Thiophenecarbaldehyde phenylhydrazone

Base Information

• Chemical Name: 2-Thiophenecarbaldehyde phenylhydrazone
• CAS No.: 39677-96-8
• Molecular Formula: C11H10N2S
• Molecular Weight: 202.28
• Hs Code.: 2934999090
• European Community (EC) Number: 661-944-2
• Mol file: 39677-96-8.mol

Synonyms:2-thiophenecarbaldehyde phenylhydrazone;39677-96-8;thiophene-2-carbaldehyde 2-phenylhydrazone;N-[(E)-thiophen-2-ylmethylideneamino]aniline;SCHEMBL3067385;CCG-50405;AKOS024339949;N-Phenyl-N'-(thiophen-2-ylmethylene)hydrazine;SR-01000639786-1

Chemical Property of 2-Thiophenecarbaldehyde phenylhydrazone

Chemical Property:

• PSA: 52.63000
• LogP: 3.26710
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 202.05646950
• Heavy Atom Count: 14
• Complexity: 188

Purity/Quality:

99% ^*data from raw suppliers

2-THIOPHENECARBOXALDEHYDE PHENYLHYDRAZONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)NN=CC2=CC=CS2
• Isomeric SMILES: C1=CC=C(C=C1)N/N=C/C2=CC=CS2

Technology Process of 2-Thiophenecarbaldehyde phenylhydrazone

There total 11 articles about 2-Thiophenecarbaldehyde phenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

thiophene-2-carbaldehyde (98-03-3) + phenylhydrazine (100-63-0) → 1-(thiophen-2-ylmethylene)-2-phenylhydrazine (39677-96-8)

Guidance literature:

In neat (no solvent); at 20 ℃; for 0.00222222h;

DOI:10.1016/j.molcata.2014.06.024

Reference yield: 95.0%

thiophene-2-carbaldehyde (98-03-3) + phenylhydrazine hydrochloride (59-88-1) → 1-(thiophen-2-ylmethylene)-2-phenylhydrazine (39677-96-8)

Guidance literature:

With sodium acetate; In ethanol; at 80 ℃; for 0.0833333h; Microwave irradiation; air-cooling;

DOI:10.1021/co100015b

Reference yield: 92.0%

4,5-dihidro-4-hydroxy-5-phenyl-5,6,4-diazabora-benzo{b}thiophene 4,5-dihydro-4-hydroxy-5-phenyl-5,6,4-diazabora-benzo{b}thiophen (4347-34-6) → 1-(thiophen-2-ylmethylene)-2-phenylhydrazine (39677-96-8)

Guidance literature:

With sodium hydroxide; In not given; with 2N NaOH, 2 h;

upstream raw materials:

phenylhydrazine

2,2-Dichloro-3-hydroxy-3-thiophen-2-yl-propionic acid propyl ester

thiophene-2-carbaldehyde

2-Acetylthiophene

Downstream raw materials:

4-(2-thienyl)-2,7-diphenyl-6,8-dioxo-2,3,7-triazabicyclo<3.3.0>oct-3-ene

Phenyl-[(4,5,6,7-tetrahydro-benzo[1,3]dithiol-2-ylidene)-thiophen-2-yl-methyl]-diazene

thiophene-2-carbonitrile

N,N-dimethyl-N'-phenylcarbamimidic chloride