METHYL B-(P-NITROPHENYL)METHACRYLATE

Base Information

• Chemical Name: METHYL B-(P-NITROPHENYL)METHACRYLATE
• CAS No.: 40277-76-7
• Molecular Formula: C11H11NO4
• Molecular Weight: 221.213
• Hs Code.: 2916399090
• Mol file: 40277-76-7.mol

Synonyms:2-Methyl-3t-(4-nitro-phenyl)-acrylsaeure-methylester;2-methyl-3t-(4-nitro-phenyl)-acrylic acid methyl ester;2-Propenoic acid,2-methyl-3-(4-nitrophenyl)-,methyl ester;

Chemical Property of METHYL B-(P-NITROPHENYL)METHACRYLATE

Chemical Property:

• PSA: 72.12000
• LogP: 2.69430

Purity/Quality:

99% ^*data from raw suppliers

METHYL-B-(PARA-NITROPHENYL)METHACRYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL B-(P-NITROPHENYL)METHACRYLATE

There total 19 articles about METHYL B-(P-NITROPHENYL)METHACRYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

p-nitrobenzene iodide (636-98-6) + methacrylic acid methyl ester (80-62-6,114512-63-9,143476-91-9,25188-98-1,9011-14-7) → methyl (E)-2-methyl-3-(4-nitrophenyl)acrylate (40277-76-7,37542-78-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 3h; Inert atmosphere;

DOI:10.1007/s10562-021-03767-6

Reference yield: 92.0%

4-nitrobenzaldehdye (555-16-8) + methyl 2-(triphenylphosphoranylidene)propionate (2605-68-7) → methyl (E)-2-methyl-3-(4-nitrophenyl)acrylate (40277-76-7,37542-78-2)

Guidance literature:

In dichloromethane; at 20 ℃; for 12h; Inert atmosphere; Cooling with ice;

Reference yield: 91.0%

ethyl 2-diethoxyphosphorylpropionate (3699-66-9) + 4-nitrobenzaldehdye (555-16-8) → methyl (E)-2-methyl-3-(4-nitrophenyl)acrylate (40277-76-7,37542-78-2)

Guidance literature:

ethyl 2-diethoxyphosphorylpropionate; With sodium hydride; In tetrahydrofuran; for 0.25h; Inert atmosphere;

4-nitrobenzaldehdye; In tetrahydrofuran; at 20 ℃; for 10h; Inert atmosphere;

DOI:10.1016/j.bmcl.2021.128106

upstream raw materials:

ethanol

(E)-2-methyl-3-(4-nitrophenyl)acrylic acid

(E)-2-methyl-3-(4-nitrophenyl)acrylaldehyde

methanol

Downstream raw materials:

(E)-2-methyl-3-(4-nitrophenyl)acrylic acid

C₃₄H₃₅N₃O₄S

C₃₃H₃₄N₄O₄S

C₃₅H₃₆N₄O₄