3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE

Base Information Edit

Chemical Name:3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE
CAS No.:40733-27-5
Molecular Formula:C16H28N2O5Si
Molecular Weight:356.494
Hs Code.:
Mol file:40733-27-5.mol

Synonyms:TBS-T;3'-DiTBSRiboT;

Suppliers and Price of 3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3''-O-(TBDMS)Thymidine
10mg
$ 60.00

CSNpharm
3'-O-(TBDMS)Thymidine
25mg
$ 35.00

CSNpharm
3'-O-(TBDMS)Thymidine
1mg
$ 20.00

CSNpharm
3'-O-(TBDMS)Thymidine
100mg
$ 65.00

Crysdot
1-((2R,4S,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 97%
1g
$ 301.00

Chemenu
1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 97%
1g
$ 284.00

Biosynth Carbosynth
3’-O-t-Bulyldimethylsilyl thymidine
250 mg
$ 162.50

Biosynth Carbosynth
3’-O-t-Bulyldimethylsilyl thymidine
500 mg
$ 250.00

Biosynth Carbosynth
3’-O-t-Bulyldimethylsilyl thymidine
100 mg
$ 100.00

Biosynth Carbosynth
3’-O-t-Bulyldimethylsilyl thymidine
25 mg
$ 50.00

Total 12 raw suppliers

Chemical Property of 3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE Edit

Chemical Property:

Melting Point:93-94 °C
PKA:9.55±0.10(Predicted)
PSA：93.55000
Density:1.17±0.1 g/cm3(Predicted)
LogP:1.51520
Storage Temp.:2-8°C

Purity/Quality:

98%, ^*data from raw suppliers

3''-O-(TBDMS)Thymidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description 3'-O-[tert-Butyl(dimethyl)silyl]thymidine is a nucleoside analog that is chemically stable and has been shown to be a potential biomarker for the diagnosis of fetal bovine spongiform encephalopathy (BSE). 3'-O-t-Bulyldimethylsilyl thymidine binds to basic proteins in the cell nucleus and has been shown to inhibit protein synthesis in tubule cells of the kidney and skin cancer cells.

Technology Process of 3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE

There total 4 articles about 3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 40733-26-4
3',5'-O-di(tert-butyldimethylsilyl)thymidine

: 40733-27-5
3'-O-(t-butyldimethylsilyl)thymidine

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

Guidance literature:: With phosphomolybdic acid; In methanol; at 20 ℃; for 3h; Solvent; Reagent/catalyst; regioselective reaction;
DOI:10.1055/s-0037-1610300