4-[3-(Trifluoromethyl)phenoxy]aniline

Base Information

Chemical Name:4-[3-(Trifluoromethyl)phenoxy]aniline
CAS No.:41605-31-6
Molecular Formula:C13H10F3NO
Molecular Weight:253.224
Hs Code.:2922299090
European Community (EC) Number:844-314-3
DSSTox Substance ID:DTXSID50375336
Wikidata:Q82163865
Mol file:41605-31-6.mol

Synonyms:41605-31-6;4-[3-(trifluoromethyl)phenoxy]aniline;4-(3-Trifluoromethylphenoxy)aniline;4-(3-(Trifluoromethyl)phenoxy)aniline;Benzenamine, 4-[3-(trifluoromethyl)phenoxy]-;4-[3-(trifluoromethyl)phenoxy]phenylamine;SCHEMBL476378;DTXSID50375336;MFCD00170931;4-(3'-trifluoromethylphenoxy)-aniline;AKOS000213940;MS-6694;4-[3-(trifluoromethyl)phenoxy]benzenamine;CS-0217708;EN300-82917;C78212;Z330805416

Suppliers and Price of 4-[3-(Trifluoromethyl)phenoxy]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(3-Trifluoromethylphenoxy)aniline 95+%
1g
$ 327.00

American Custom Chemicals Corporation
4-(3-TRIFLUOROMETHYLPHENOXY)ANILINE 95.00%
5MG
$ 502.89

AK Scientific
4-[3-(Trifluoromethyl)phenoxy]aniline
250mg
$ 197.00

Acrotein
4-(3-(Trifluoromethyl)phenoxy)aniline 97%
0.25g
$ 146.67

Total 5 raw suppliers

Chemical Property of 4-[3-(Trifluoromethyl)phenoxy]aniline

Chemical Property:

Vapor Pressure:0.00029mmHg at 25°C
Boiling Point:321.9oC at 760 mmHg
Flash Point:148.5oC
PSA：35.25000
Density:1.293g/cm3
LogP:4.66110
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:253.07144843
Heavy Atom Count:18
Complexity:262

Purity/Quality:

98% ^*data from raw suppliers

4-(3-Trifluoromethylphenoxy)aniline 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC2=CC=C(C=C2)N)C(F)(F)F

Technology Process of 4-[3-(Trifluoromethyl)phenoxy]aniline

There total 7 articles about 4-[3-(Trifluoromethyl)phenoxy]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 2303-26-6
1-nitro-4-(3-(trifluoromethyl)phenoxy)benzene

: 41605-31-6
4-[3-(trifluoromethyl)-phenoxy]aniline

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 15h;
DOI:10.1016/j.bmc.2018.03.031

Reference yield:

: 100-00-5
4-chlorobenzonitrile

: 41605-31-6
4-[3-(trifluoromethyl)-phenoxy]aniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 100 °C

2: palladium on activated charcoal; hydrogen / methanol / 15 h / 20 °C

With palladium on activated charcoal; hydrogen; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2018.03.031

Reference yield:

: 98-17-9
3-Trifluoromethylphenol

: 41605-31-6
4-[3-(trifluoromethyl)-phenoxy]aniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 100 °C

2: palladium on activated charcoal; hydrogen / methanol / 15 h / 20 °C

With palladium on activated charcoal; hydrogen; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2018.03.031