Isoquinolinium, 3,4-dihydro-2-phenyl-, bromide

Base Information

• Chemical Name: Isoquinolinium, 3,4-dihydro-2-phenyl-, bromide
• CAS No.: 41852-27-1
• Molecular Formula: C15H14N.Br
• Molecular Weight: 288.187
• Mol file: 41852-27-1.mol

Synonyms:

Chemical Property of Isoquinolinium, 3,4-dihydro-2-phenyl-, bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Isoquinolinium, 3,4-dihydro-2-phenyl-, bromide

There total 7 articles about Isoquinolinium, 3,4-dihydro-2-phenyl-, bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-phenyl-1,2,3,4-tetrahydroisoquinoline (3340-78-1) → 2-phenyl-3,4-dihydroisoquinolin-2-ium bromide (41852-27-1)

Guidance literature:

With tris(2,2'-bipyridyl)ruthenium dichloride; Bromotrichloromethane; In N,N-dimethyl-formamide; for 16h; Irradiation;

DOI:10.1039/c8gc01730a

Reference yield: 73.0%

2-(2-bromoethyl)benzaldehyde (22901-09-3) + aniline (62-53-3) → 2-phenyl-3,4-dihydroisoquinolin-2-ium bromide (41852-27-1)

Guidance literature:

In ethyl acetate;

Reference yield:

isochromane (493-05-0) → 2-phenyl-3,4-dihydroisoquinolin-2-ium bromide (41852-27-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: bromine / CCl₄ / 1 h / Heating

1.2: hydrobromic acid / H₂O / 0.25 h / Heating

2.1: dioxane

With bromine; In 1,4-dioxane; tetrachloromethane;

DOI:10.1016/j.tetasy.2006.02.007

upstream raw materials:

2-(2-bromoethyl)benzaldehyde

aniline

isochromane

2-phenyl-1,2,3,4-tetrahydroisoquinoline

Downstream raw materials:

1,2,3,4-tetrahydro-2-phenylisoquinolin-1-yl-1-phosphonic acid diethyl ester

1,2,3,4-tetrahydro-1-(nitromethyl)-2-phenylisoquinoline

2-phenyl-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile