1-cyano-N-phenyl-1,2,3,4-tetrahydroisoquinoline

Base Information

Chemical Name:1-cyano-N-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS No.:55662-89-0
Molecular Formula:C16H14N2
Molecular Weight:234.301
Hs Code.:2933499090
DSSTox Substance ID:DTXSID50461288
Nikkaji Number:J1.780.062K
Mol file:55662-89-0.mol

Synonyms:55662-89-0;1-cyano-N-phenyl-1,2,3,4-tetrahydroisoquinoline;2-phenyl-3,4-dihydro-1H-isoquinoline-1-carbonitrile;2-Phenyl-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile;SCHEMBL6671821;DTXSID50461288;JFDUBCIPPATLNR-UHFFFAOYSA-N

Suppliers and Price of 1-cyano-N-phenyl-1,2,3,4-tetrahydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-cyano-N-phenyl-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Melting Point:101-102℃
PSA：27.03000
LogP:3.37898
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:234.115698455
Heavy Atom Count:18
Complexity:323

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C(C2=CC=CC=C21)C#N)C3=CC=CC=C3

Technology Process of 1-cyano-N-phenyl-1,2,3,4-tetrahydroisoquinoline

There total 38 articles about 1-cyano-N-phenyl-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 3340-78-1
2-phenyl-1,2,3,4-tetrahydroisoquinoline

: 7677-24-9
trimethylsilyl cyanide

: 55662-89-0
2-phenyl-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile

Guidance literature:: With tert.-butylhydroperoxide; [(bpy)AuCl₂]Cl; In methanol; decane; at 20 ℃; for 5h; regioselective reaction;
DOI:10.1039/c0cc03844j

Reference yield: 97.0%

: potassium cyanide

: 3340-78-1
2-phenyl-1,2,3,4-tetrahydroisoquinoline

: 55662-89-0
2-phenyl-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile

Guidance literature:: With [Ir(tbp-py)2(bpy)]PF₆; acetic acid; In acetonitrile; for 20h; Irradiation;
DOI:10.1039/c1cc15643h

Reference yield: 95.0%

: 3340-78-1
2-phenyl-1,2,3,4-tetrahydroisoquinoline

: 78-67-1
2,2'-azobis(isobutyronitrile)

: 55662-89-0
2-phenyl-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile

Guidance literature:: With tetrabutylammomium bromide; In acetonitrile; at 20 ℃; for 3h; Electrochemical reaction; Green chemistry;
DOI:10.1039/d1ob01416a