7-Isopropyl-2,4-dimethylazulene

Base Information

• Chemical Name: 7-Isopropyl-2,4-dimethylazulene
• CAS No.: 492-45-5
• Molecular Formula: C15H18
• Molecular Weight: 198.308
• Mol file: 492-45-5.mol

Synonyms:7-Isopropyl-2,4-dimethyl-azulen;7-isopropyl-2,4-dimethyl-azulene;Se-guaiazulene;Se-Guajazulen;Se-Guaiazulen;2.4-Dimethyl-7-isopropyl-azulen;

Chemical Property of 7-Isopropyl-2,4-dimethylazulene

Chemical Property:

• PSA: 0.00000
• LogP: 4.53160

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Isopropyl-2,4-dimethylazulene

There total 13 articles about 7-Isopropyl-2,4-dimethylazulene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-7-isopropyl-2,4-dimethyl-azulene → 7-isopropyl-2,4-dimethylazulene (492-45-5)

Guidance literature:

With palladium diacetate; poly(methylhydrosiloxane);

DOI:10.1002/anie.200501276

Reference yield:

(8S,8aR)-3-Chloro-5-isopropyl-8-methyl-8,8a-dihydro-1H-azulen-2-one → 7-isopropyl-2,4-dimethylazulene (492-45-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: Burgess reagent

1.2: p-chloranil

2.1: poly(methylhydrosiloxane); Pd(OAc)2

With palladium diacetate; Burgess Reagent; poly(methylhydrosiloxane);

DOI:10.1002/anie.200501276

Reference yield:

(8S,8aR)-3-Chloro-5-isopropyl-2,8-dimethyl-1,2,8,8a-tetrahydro-azulen-2-ol → 7-isopropyl-2,4-dimethylazulene (492-45-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Burgess reagent

1.2: p-chloranil

2.1: poly(methylhydrosiloxane); Pd(OAc)2

With palladium diacetate; Burgess Reagent; poly(methylhydrosiloxane);

DOI:10.1002/anie.200501276

upstream raw materials:

isopropyllithium

3-Cyano-7-isopropyl-2,4-dimethylazulen

3-Carbamoyl-7-isopropyl-2,4-dimethylazulen

3-Cyano-7-isopropyl-2,4-dimethylazulen-1-carboxysaeure

Downstream raw materials:

7-isopropyl-2,4-dimethyl-azulene-1-carboxylic acid anilide

oxalic acid

acetic acid

acetone