Carbamic acid, [(1S)-2-[(2S,4S)-2-(aminocarbonyl)-4-fluoro-1-pyrrolidinyl]-1-cyclohexyl- 2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester

Base Information

Chemical Name:Carbamic acid, [(1S)-2-[(2S,4S)-2-(aminocarbonyl)-4-fluoro-1-pyrrolidinyl]-1-cyclohexyl- 2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester
CAS No.:426844-69-1
Molecular Formula:C28H32FN3O4
Molecular Weight:493.578
Hs Code.:
Mol file:426844-69-1.mol

Synonyms:

Suppliers and Price of Carbamic acid, [(1S)-2-[(2S,4S)-2-(aminocarbonyl)-4-fluoro-1-pyrrolidinyl]-1-cyclohexyl- 2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, [(1S)-2-[(2S,4S)-2-(aminocarbonyl)-4-fluoro-1-pyrrolidinyl]-1-cyclohexyl- 2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [(1S)-2-[(2S,4S)-2-(aminocarbonyl)-4-fluoro-1-pyrrolidinyl]-1-cyclohexyl- 2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester

There total 1 articles about Carbamic acid, [(1S)-2-[(2S,4S)-2-(aminocarbonyl)-4-fluoro-1-pyrrolidinyl]-1-cyclohexyl- 2-oxoethyl]-, 9H-fluoren-9-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 161321-36-4,198543-96-3
S-(((9H-fluoren-9-yl)methoxy)carbonyl)cyclohexylglycine

: 426844-23-7
(2S,4S)-4-fluoropyrrolidine-2-carboxamide hydrochloride

: 426844-69-1
(4S)-1-((2S)-2-cyclohexyl-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]-amino}acetyl)-4-fluoro-L-prolinamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; Cooling with ice;
DOI:10.1248/cpb.56.1110

Reference yield: 92.0%

: 426844-69-1
(4S)-1-((2S)-2-cyclohexyl-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]-amino}acetyl)-4-fluoro-L-prolinamide

: 426844-70-4
9H-fluoren-9-ylmethyl {(1S)-2-[(2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl}carbamate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; trifluoroacetic anhydride; In tetrahydrofuran; for 1h; Cooling with ice;
DOI:10.1248/cpb.56.1110