8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-methyl-6-phenyl-

Base Information

Chemical Name:8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-methyl-6-phenyl-
CAS No.:103344-16-7
Molecular Formula:C₁₄H₉N₃OS₂
Molecular Weight:299.377
Hs Code.:
DSSTox Substance ID:DTXSID60145789
Wikidata:Q83010421

Synonyms:BRN 5588784;8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-methyl-6-phenyl-;103344-16-7;2-Methyl-6-phenyl-8H-(1,3,4)thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one;DTXSID60145789

Suppliers and Price of 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-methyl-6-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-methyl-6-phenyl-

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:299.01870427
Heavy Atom Count:20
Complexity:499

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN2C(=O)C3=C(N=C2S1)SC(=C3)C4=CC=CC=C4

Technology Process of 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-methyl-6-phenyl-

There total 4 articles about 8H-(1,3,4)Thiadiazolo(3,2-a)thieno(2,3-d)pyrimidin-8-one, 2-methyl-6-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 53645-94-6
2-chloro-5-methyl-1,3,4-thiadiazole

: 4815-34-3
ethyl 2-amino-5-phenylthiophene-3-carboxylate

: 103344-16-7
2-methyl-6-phenyl-8H-<1,3,4>thiadiazolo<3,2-a>thieno<2,3-d>pyrimidin-8-one

Guidance literature:: at 160 ℃;

Reference yield: 47.0%

: 64-19-7,77671-22-8
acetic acid

: 155054-32-3
2,3-dihydro-3-amino-6-phenyl-2-thioxothieno<2,3-d>pyrimidin-4(1H)-one

: 103344-16-7
2-methyl-6-phenyl-8H-<1,3,4>thiadiazolo<3,2-a>thieno<2,3-d>pyrimidin-8-one

Guidance literature:: With methanesulfonic acid; phosphorus pentoxide; at 80 ℃; for 9h;

Reference yield:

: 85716-86-5
2-isothiocyanato-5-phenyl-3-thiophenecarboxylic acid ethyl ester

: 103344-16-7
2-methyl-6-phenyl-8H-<1,3,4>thiadiazolo<3,2-a>thieno<2,3-d>pyrimidin-8-one

Guidance literature:: Multi-step reaction with 3 steps

1: 40 percent / NH₂NH₂*H₂O / CH₂Cl₂ / 2 h / Ambient temperature

2: 1.) KOH, 2.) 37percent HCl / ethanol / 0.5 h / Heating

3: 47 percent / CH₃SO₃H, P₂O₅ / 9 h / 80 °C

With hydrogenchloride; potassium hydroxide; methanesulfonic acid; phosphorus pentoxide; hydrazine hydrate; In ethanol; dichloromethane;