Acetyl isocyanate, phenoxy-

Base Information

• Chemical Name: Acetyl isocyanate, phenoxy-
• CAS No.: 4461-31-8
• Molecular Formula: C9H7NO3
• Molecular Weight: 177.159
• Mol file: 4461-31-8.mol

Synonyms:

Chemical Property of Acetyl isocyanate, phenoxy-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetyl isocyanate, phenoxy-

There total 2 articles about Acetyl isocyanate, phenoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxalyl dichloride (79-37-8) + phenoxyacetamide (621-88-5) → phenoxyacetyl isocyanate (4461-31-8)

Guidance literature:

In 1,2-dichloro-ethane;

DOI:10.1021/jo01023a501

Reference yield:

→ phenoxyacetyl isocyanate (4461-31-8)

Guidance literature:

α-Phenoxyacetylchlorid, Isocyanatotrimethylsilan (/BRN= 744962/);

Reference yield: 82.3%

phenoxyacetyl isocyanate (4461-31-8) + N-hydroxy-2,2-diphenylacetimidoyl chloride (4467-90-7) → C23H19ClN2O4

Guidance literature:

In toluene; for 2h; Heating;

upstream raw materials:

oxalyl dichloride

phenoxyacetamide

Downstream raw materials:

morpholine-4-carboxylic acid 2-phenoxy-acetylamide

N-Phenyloxyacetyl-O-methylcarbamat

N-Phenyloxyacetyl-O-n-propylcarbamat

N-(Phenoxyacetyl)-peroxycarbamidsaeure-tert-butylester

Refernces

• 1、 Naito,Nakagawa,Okumura,Konishi,Kawaguchi. "Synthesis of 6-aminopenicillanic acid derivatives. I. 6-(Acylureido) penicillanates and some related compounds.". . p. 145 - 157. Retrieved 2007/10/05.