2-Fluoro-3-iodobenzoic acid

Base Information

Chemical Name:2-Fluoro-3-iodobenzoic acid
CAS No.:447464-03-1
Molecular Formula:C7H4FIO2
Molecular Weight:266.01
Hs Code.:2916399090
European Community (EC) Number:805-049-9
DSSTox Substance ID:DTXSID30453565
Wikidata:Q72473549
Mol file:447464-03-1.mol

Synonyms:2-Fluoro-3-iodobenzoic acid;447464-03-1;BENZOIC ACID, 2-FLUORO-3-IODO-;MFCD07774248;2-fluoro-3-iodo-benzoic Acid;SCHEMBL363107;DTXSID30453565;FVLHWICBHZCKED-UHFFFAOYSA-N;2-FLUORO-3-IODOBENZOICACID;CL8043;AKOS015919935;AM62553;CS-W006030;GS-4034;2-Fluoro-3-iodobenzoic acid, AldrichCPR;SY107047;FT-0691674;A20336;EN300-123551;J-509369;Z1269149504

Suppliers and Price of 2-Fluoro-3-iodobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-3-iodobenzoicAcid
100mg
$ 75.00

SynQuest Laboratories
2-Fluoro-3-iodobenzoic acid
1 g
$ 45.00

Crysdot
2-Fluoro-3-iodobenzoicacid 95+%
25g
$ 495.00

Crysdot
2-Fluoro-3-iodobenzoicacid 95+%
10g
$ 219.00

Chemenu
2-Fluoro-3-iodobenzoicacid 95%
5g
$ 141.00

Chemenu
2-Fluoro-3-iodobenzoicacid 95%
25g
$ 468.00

Chemenu
2-Fluoro-3-iodobenzoicacid 95%
10g
$ 207.00

Apolloscientific
2-Fluoro-3-iodobenzoicacid
25g
$ 565.00

Apolloscientific
2-Fluoro-3-iodobenzoicacid
5g
$ 160.00

Apolloscientific
2-Fluoro-3-iodobenzoicacid
1g
$ 44.00

Total 31 raw suppliers

Chemical Property of 2-Fluoro-3-iodobenzoic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:331.018oC at 760 mmHg
PKA:2.92±0.10(Predicted)
Flash Point:153.994oC
PSA：37.30000
Density:2.074g/cm3
LogP:2.12850
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:265.92401
Heavy Atom Count:11
Complexity:163

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-3-iodobenzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)I)F)C(=O)O

Technology Process of 2-Fluoro-3-iodobenzoic acid

There total 3 articles about 2-Fluoro-3-iodobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 211943-27-0
2-fluoro-3-iodobenzonitrile

: 447464-03-1
2-fluoro-3-iodobenzoic acid

Guidance literature:: With sulfuric acid; water; In 1,4-dioxane; at 115 ℃; for 4h;

Reference yield: 68.0%

: 124-38-9,18923-20-1
carbon dioxide

: 348-52-7
1-Fluoro-2-iodobenzene

: 447464-03-1
2-fluoro-3-iodobenzoic acid

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -75 ℃;
DOI:10.1002/1099-0690(200210)2002:19<3351::AID-EJOC3351>3.0.CO;2-I

Reference yield:

: 394-47-8
2-fluorobenzonitrile

: 447464-03-1
2-fluoro-3-iodobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2,2,6,6-tetramethylpiperidinyl-lithium; iodine / tetrahydrofuran / -78 - 20 °C

2: sulfuric acid / 1,4-dioxane / 115 °C

With sulfuric acid; 2,2,6,6-tetramethylpiperidinyl-lithium; iodine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.bmcl.2011.09.006