Guanidine

Base Information

• Chemical Name: Guanidine
• CAS No.: 113-00-8
• Deprecated CAS: 113978-92-0,113978-93-1,117365-55-6,152252-01-2,475470-57-6
• Molecular Formula: CH5 N3
• Molecular Weight: 59.0708
• European Community (EC) Number: 204-021-8
• UNII: JU58VJ6Y3B
• DSSTox Substance ID: DTXSID0023117
• Nikkaji Number: J2.462G
• Wikipedia: Guanidine
• Wikidata: Q183309
• NCI Thesaurus Code: C77851
• Pharos Ligand ID: Q3HSJJ1A3X3U
• Metabolomics Workbench ID: 37883
• ChEMBL ID: CHEMBL821
• Mol file: 113-00-8.mol

Synonyms:Chloride, Guanidinium;Chloride, Guanidium;Guanidine;Guanidine Hydrochloride;Guanidine Monohydrate;Guanidine Monohydrobromide;Guanidine Monohydrochloride;Guanidine Monohydroiodine;Guanidine Nitrate;Guanidine Phosphate;Guanidine Sulfate;Guanidine Sulfate (1:1);Guanidine Sulfate (2:1);Guanidine Sulfite (1:1);Guanidinium;Guanidinium Chloride;Guanidium Chloride;Hydrochloride, Guanidine;Monohydrate, Guanidine;Monohydrobromide, Guanidine;Monohydrochloride, Guanidine;Monohydroiodine, Guanidine;Nitrate, Guanidine;Phosphate, Guanidine;Sulfate, Guanidine

Chemical Property of Guanidine

Chemical Property:

• Vapor Pressure: 8.67mmHg at 25°C
• Boiling Point: 132.9°Cat760mmHg
• Flash Point: 34.2°C
• PSA: 75.89000
• Density: 1.55g/cm³
• LogP: 0.33890
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 59.048347172
• Heavy Atom Count: 4
• Complexity: 26.3

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: C(=N)(N)N

Technology Process of Guanidine

There total 110 articles about Guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenyl-p-toluidino-methanesulfonic acid ; compound with guanidine → benzaldehyde (100-52-7) + p-toluidine (106-49-0,12221-03-3) + guanidine nitrate (113-00-8)

Guidance literature:

Reference yield:

(+/-)-anilino-phenyl-methanesulfonic acid ; guanidine salt → benzaldehyde (100-52-7) + guanidine nitrate (113-00-8) + aniline (62-53-3)

Guidance literature:

Reference yield:

nitrosoguanidine (674-81-7) → cis-nitrous acid (7782-77-6) + guanidine nitrate (113-00-8)

Guidance literature:

beim Kochen;

upstream raw materials:

CYANAMID

methylamine hydrochloride

N₁-methyl biguanide hydrochloride

N-Cyanoguanidine

Downstream raw materials:

8-amino-1,7-dihydro-purine-6-thione

8-amino-1,7-dihydro-purin-6-one

1-phenyl-3-guanylthiourea

N-(4-bromo-phenyl)-N'-carbamimidoyl-thiourea

Refernces

• 1、 Brennauer, Albert,Keller, Max,Freund, Matthias,Bernhardt, Günther,Buschauer, Armin. "Decomposition of 1-(ω-aminoalkanoyl)guanidines under alkaline conditions". . p. 6996 - 6999. Retrieved 2007.
• 2、 Kapeller. "-". . p. 1652. Retrieved 1926.
• 3、 Strecker. "-". . p. 155. Retrieved 1861.
• 4、 Gagnon et al.. "-". . p. 520,521, 524. Retrieved 1959.
• 5、 Ewan,Young. "-". . . Retrieved 1921.
• 6、 Boivin. "-". . p. 827. Retrieved 1956.
• 7、 -. "Tin (II) cluster compound, and preparation method and application thereof". Paragraph 0019; 0021-0022; 0024-0025; 0027-0028; 0030-0031;. . Retrieved 2020/06/09.
• 8、 Mattia Bizzarri, Bruno,Botta, Lorenzo,Pérez-Valverde, Maritza Iveth,Saladino, Raffaele,Di Mauro, Ernesto,García-Ruiz, Juan Manuel. "Silica Metal Oxide Vesicles Catalyze Comprehensive Prebiotic Chemistry". . p. 8126 - 8132. Retrieved 2018/05/29.