1-Phenyl-3-(pyrrolidin-1-YL)propan-1-OL

Base Information

Chemical Name:1-Phenyl-3-(pyrrolidin-1-YL)propan-1-OL
CAS No.:4641-67-2
Molecular Formula:C13H19NO
Molecular Weight:205.29600
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10499481
Mol file:4641-67-2.mol

Synonyms:1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL;4641-67-2;DTXSID10499481;AKOS011905639

Suppliers and Price of 1-Phenyl-3-(pyrrolidin-1-YL)propan-1-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL 98.00%
5MG
$ 495.50

Total 3 raw suppliers

Chemical Property of 1-Phenyl-3-(pyrrolidin-1-YL)propan-1-OL

Chemical Property:

PSA：23.47000
LogP:2.14380
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:205.146664230
Heavy Atom Count:15
Complexity:171

Purity/Quality:

97% ^*data from raw suppliers

1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CCC(C2=CC=CC=C2)O

Technology Process of 1-Phenyl-3-(pyrrolidin-1-YL)propan-1-OL

There total 6 articles about 1-Phenyl-3-(pyrrolidin-1-YL)propan-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 94-39-3
1-phenyl-3-(pyrrolidin-1-yl)propan-1-one

: 4641-67-2
1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol

Guidance literature:: With sodium tetrahydroborate; In methanol;

Reference yield: 57.0%

: 123-75-1
pyrrolidine

: 62872-58-6
3-iodo-1-phenyl-propan-1-ol

: 4641-67-2
1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol

Guidance literature:: In tetrahydrofuran; for 4h; Inert atmosphere; Reflux;
DOI:10.1248/bpb.34.538

Reference yield:

: 936-59-4
3-chloropropiophenone

: 4641-67-2
1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 24 h / 20 °C / Inert atmosphere

2: sodium iodide / acetone / 48 h / Inert atmosphere; Reflux

3: tetrahydrofuran / 4 h / Inert atmosphere; Reflux

With sodium tetrahydroborate; sodium iodide; In tetrahydrofuran; methanol; acetone; 2: Finkelstein reaction;
DOI:10.1248/bpb.34.538