N-(4-sulfamoylphenyl)propanamide

Base Information

• Chemical Name: N-(4-sulfamoylphenyl)propanamide
• CAS No.: 4708-37-6
• Molecular Formula: C₉H₁₂N₂O₃S
• Molecular Weight: 228.272
• UNII: 6Q424VDF6Z
• Pharos Ligand ID: 18KV8YCWWST3
• ChEMBL ID: CHEMBL278395
• Mol file: 4708-37-6.mol

Synonyms:N-(4-sulfamoylphenyl)propanamide;CHEMBL278395;4708-37-6;N-[4-(aminosulfonyl)phenyl]propanamide;WGY;N-(4-Sulfamoyl-phenyl)-propionamide;6Q424VDF6Z;SCHEMBL13263684;4-Propionamido-benzenesulfonamide;aromatic sulfonamide compound 10;BDBM16645;N-(4-Sulfamoylphenyl)propionamide;AKOS003252339;CCG-282140;Propanamide, N-[4-(aminosulfonyl)phenyl]-;CS-0231805;EN300-1255176;AO-080/11989809;Z27682767

Chemical Property of N-(4-sulfamoylphenyl)propanamide

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 228.05686342
• Heavy Atom Count: 15
• Complexity: 313

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(=O)NC1=CC=C(C=C1)S(=O)(=O)N

Technology Process of N-(4-sulfamoylphenyl)propanamide

There total 4 articles about N-(4-sulfamoylphenyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-propionyl-sulfanilyl chloride (7139-88-0) → N-propionyl-sulfanilic acid amide (4708-37-6)

Guidance literature:

With ammonium hydroxide;

DOI:10.1021/ja01878a022

Reference yield:

propionyl chloride (79-03-8) + sulfanilamide (63-74-1) → N-propionyl-sulfanilic acid amide (4708-37-6)

Guidance literature:

With sodium hydroxide; at 20 ℃;

DOI:10.1021/jm031057+

Reference yield:

N-(phenyl)-2-methylacetamide (620-71-3) → N-propionyl-sulfanilic acid amide (4708-37-6)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfuric acid

2: aqueous ammonia

With ammonium hydroxide; chlorosulphuric acid;

DOI:10.1021/ja01878a022

upstream raw materials:

N-propionyl-sulfanilyl chloride

propionic acid anhydride

sulfanilamide

propionyl chloride