2-(4-Aminophenyl)-6-nitroquinoline-4-carboxylic acid

Base Information

Chemical Name:2-(4-Aminophenyl)-6-nitroquinoline-4-carboxylic acid
CAS No.:475474-44-3
Molecular Formula:C16H11N3O4
Molecular Weight:309.281
Hs Code.:
DSSTox Substance ID:DTXSID90573950
Wikidata:Q82462808
Mol file:475474-44-3.mol

Synonyms:475474-44-3;2-(4-Aminophenyl)-6-nitroquinoline-4-carboxylic acid;4-Quinolinecarboxylic acid, 2-(4-aminophenyl)-6-nitro-;DTXSID90573950;2-(4-aminophenyl)-6-nitro-4-quinolinecarboxylic acid

Suppliers and Price of 2-(4-Aminophenyl)-6-nitroquinoline-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-(4-Aminophenyl)-6-nitroquinoline-4-carboxylic acid

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:309.07495584
Heavy Atom Count:23
Complexity:459

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NC3=C(C=C(C=C3)[N+](=O)[O-])C(=C2)C(=O)O)N

Technology Process of 2-(4-Aminophenyl)-6-nitroquinoline-4-carboxylic acid

There total 1 articles about 2-(4-Aminophenyl)-6-nitroquinoline-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.1%

: 611-09-6
5-nitroisatin

: 99-92-3
p-aminobenzophenone

: 475474-44-3
2-(4'-aminophenyl)-6-nitro-4-quinolinecarboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; Heating;
DOI:10.1023/A:1014783307934

Reference yield: 78.7%

: 86-92-0
3-methyl-1-(4-methylphenyl)-2-pyrazolin-5-one

: 475474-44-3
2-(4'-aminophenyl)-6-nitro-4-quinolinecarboxylic acid

: 2-{4-[N'-(3-methyl-5-oxo-1-p-tolyl-1,5-dihydro-pyrazol-4-ylidene)-hydrazino]-phenyl}-6-nitro-quinoline-4-carboxylic acid

Guidance literature:: 2-(4'-aminophenyl)-6-nitro-4-quinolinecarboxylic acid; With hydrogenchloride; sodium nitrite; at 0 ℃;

3-methyl-1-(4-methylphenyl)-2-pyrazolin-5-one; With sodium hydroxide; at 60 ℃;

With sodium hydroxide; sodium carbonate; at 5 - 8 ℃; pH=8.5;
DOI:10.1023/A:1014783307934

Reference yield: 77.2%

: 89-25-8
edaravone

: 475474-44-3
2-(4'-aminophenyl)-6-nitro-4-quinolinecarboxylic acid

: 2-{4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-pyrazol-4-ylidene)-hydrazino]-phenyl}-6-nitro-quinoline-4-carboxylic acid

Guidance literature:: 2-(4'-aminophenyl)-6-nitro-4-quinolinecarboxylic acid; With hydrogenchloride; sodium nitrite; at 0 ℃;

edaravone; With sodium hydroxide; at 60 ℃;

With sodium hydroxide; sodium carbonate; at 5 - 8 ℃; pH=8.5;
DOI:10.1023/A:1014783307934