Technology Process of 2-Pentenoic acid, 5-(4-methoxyphenyl)-, ethyl ester, (2E)-
There total 12 articles about 2-Pentenoic acid, 5-(4-methoxyphenyl)-, ethyl ester, (2E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
para-iodoanisole; allyl alcohol;
With
tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 7h;
Schlenk technique;
Inert atmosphere;
ethyl bromoacetate;
With
magnesium oxide; triphenylphosphine;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 1.5h;
Overall yield = 85 %; Overall yield = 199 mg;
Schlenk technique;
Inert atmosphere;
DOI:10.3998/ark.5550190.0013.321
- Guidance literature:
-
With
1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride;
DOI:10.1021/jo048557a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2 / Pd/C
2: H2SO4
3: LiAlH4
4: PCC
5: LiCl; DBU
With
lithium aluminium tetrahydride; sulfuric acid; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; pyridinium chlorochromate; lithium chloride;
palladium on activated charcoal;
5: Horner-Emmons olefination;
DOI:10.1021/jo048557a
