2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, methanesulfonate

Base Information

Chemical Name:2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, methanesulfonate
CAS No.:477775-57-8
Molecular Formula:C16H34O10S
Molecular Weight:418.506
Hs Code.:

Synonyms:20-methoxy-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane;20-methoxy--(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane;mPEG7-OMs;polyethyleneglycol-350 monomethylether methanesulfonate;Methanesulfonic acid 2-{2-[2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethyl ester;2,5,8,11,14,17,20-heptaoxadocosan-22-yl methanesulfonate;

Suppliers and Price of 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
m-PEG8-Ms 98%
1 G
$ 580.00

Total 11 raw suppliers

Chemical Property of 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, methanesulfonate

Chemical Property:

PSA：116.36000
LogP:0.78940

Purity/Quality:

99.9% ^*data from raw suppliers

m-PEG8-Ms 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description m-PEG8-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

Technology Process of 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, methanesulfonate

There total 7 articles about 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol, methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4437-01-8
3,6,9,12,15,18,21-heptaoxadocosan-1-ol

: 124-63-0
methanesulfonyl chloride

: 477775-57-8
20-methoxy-1-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;

Reference yield:

: 112-60-7
Tetraethylene glycol

: 477775-57-8
20-methoxy-1-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydroxide / 6 h

2.1: potassium hydroxide / tetrahydrofuran / 0.5 h / 60 - 70 °C

2.2: 24 h / Reflux

3.1: hydrogenchloride; pyrographite; palladium 10% on activated carbon; hydrogen / water; ethanol / 4 h / Autoclave

4.1: triethylamine / dichloromethane / 1.5 h / 0 - 30 °C

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; pyrographite; triethylamine; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; water;

Reference yield:

: 112-35-6,95507-80-5
triethylene glucol monomethyl ether

: 477775-57-8
20-methoxy-1-(methylsulfonyl)oxy-3,6,9,12,15,18-hexaoxaeicosane

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / dichloromethane / 1 h / 0 - 30 °C

2.1: potassium hydroxide / tetrahydrofuran / 0.5 h / 60 - 70 °C

2.2: 24 h / Reflux

3.1: hydrogenchloride; pyrographite; palladium 10% on activated carbon; hydrogen / water; ethanol / 4 h / Autoclave

4.1: triethylamine / dichloromethane / 1.5 h / 0 - 30 °C

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; pyrographite; triethylamine; potassium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; water;